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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
ZP
101
Zimmer Partners
New York
$2.53M -$196K -5,632 -7%
EAM
102
EFG Asset Management
Oregon
$2.52M -$143K -4,102 -5%
TIM
103
Thornburg Investment Management
New Mexico
$2.41M -$6.54M -188,014 -72%
Mirae Asset Global ETFs Holdings
104
Mirae Asset Global ETFs Holdings
Hong Kong
$2.39M -$90.7K -2,608 -3%
HS
105
HighVista Strategies
Massachusetts
$2.27M +$831K +23,903 +53%
JSSH
106
J. Safra Sarasin Holding
$2.25M +$1.41M +40,399 +145%
AA
107
ALPS Advisors
Colorado
$2.13M +$2.24M +64,392 New
State of New Jersey Common Pension Fund D
108
State of New Jersey Common Pension Fund D
New Jersey
$2.04M +$722K +20,751 +51%
SCM
109
Superstring Capital Management
New York
$2.02M -$414K -11,889 -16%
AG
110
Algert Global
California
$2M -$1.95M -55,930 -48%
MOACM
111
Mutual of America Capital Management
New York
$1.96M -$46.9K -1,348 -2%
TRSOTSOK
112
Teachers Retirement System of the State of Kentucky
Kentucky
$1.94M -$59.7K -1,717 -3%
DekaBank Deutsche Girozentrale
113
DekaBank Deutsche Girozentrale
Germany
$1.9M
IIM
114
Ironwood Investment Management
Massachusetts
$1.9M -$80.9K -2,325 -4%
SEI Investments
115
SEI Investments
Pennsylvania
$1.86M -$1.22M -34,945 -38%
IIM
116
INTECH Investment Management
Florida
$1.76M -$488K -14,038 -21%
AB
117
Amalgamated Bank
New York
$1.73M -$7.86K -226 -0.4%
Janus Henderson Group
118
Janus Henderson Group
United Kingdom
$1.64M -$35M -1,007,582 -95%
Creative Planning
119
Creative Planning
Kansas
$1.59M +$504K +14,485 +43%
State of Tennessee, Department of Treasury
120
State of Tennessee, Department of Treasury
Tennessee
$1.56M
CWM
121
Congress Wealth Management
Massachusetts
$1.52M +$631K +18,130 +65%
Royal Bank of Canada
122
Royal Bank of Canada
Ontario, Canada
$1.51M -$266K -7,656 -14%
PAM
123
Panagora Asset Management
Massachusetts
$1.47M -$94.6K -2,719 -6%
MAM
124
Monaco Asset Management
Monaco
$1.4M +$1.48M +42,500 New
YCM
125
Yousif Capital Management
Michigan
$1.36M -$16.8K -483 -1%

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.