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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Russell Investments Group
76
Russell Investments Group
United Kingdom
$5.02M +$3.56M +102,403 +207%
JF
77
Jump Financial
Illinois
$5M +$5.26M +151,290 New
GPP
78
Great Point Partners
Connecticut
$4.96M -$7.65M -220,000 -59%
Retirement Systems of Alabama
79
Retirement Systems of Alabama
Alabama
$4.82M +$81K +2,330 +2%
Citigroup
80
Citigroup
New York
$4.79M -$5.59M -160,758 -53%
MCP
81
Mirador Capital Partners
California
$4.77M +$1.57M +45,222 +46%
Deutsche Bank
82
Deutsche Bank
Germany
$4.75M -$513K -14,736 -9%
California Public Employees Retirement System
83
California Public Employees Retirement System
California
$4.71M +$484K +13,911 +11%
Invesco
84
Invesco
Georgia
$4.5M -$12.7M -365,570 -73%
RAM
85
Readystate Asset Management
Illinois
$4.37M -$555K -15,951 -11%
MIM
86
MetLife Investment Management
New Jersey
$4.36M +$67.2K +1,932 +1%
Qube Research & Technologies (QRT)
87
Qube Research & Technologies (QRT)
United Kingdom
$4.02M +$160K +4,602 +4%
EAM
88
Exome Asset Management
New York
$3.83M +$429K +12,334 +12%
New York State Teachers Retirement System (NYSTRS)
89
New York State Teachers Retirement System (NYSTRS)
New York
$3.78M +$13.9K +400 +0.4%
Jane Street
90
Jane Street
New York
$3.51M -$22.6M -649,598 -86%
RPAM
91
Rhenman & Partners Asset Management
Sweden
$3.44M
California State Teachers Retirement System (CalSTRS)
92
California State Teachers Retirement System (CalSTRS)
California
$3.42M +$4.28K +123 +0.1%
TCM
93
Tang Capital Management
California
$3.3M
Wells Fargo
94
Wells Fargo
California
$3.15M +$744K +21,384 +29%
Macquarie Group
95
Macquarie Group
Australia
$2.77M +$329K +9,466 +13%
SBH
96
Segall Bryant & Hamill
Illinois
$2.77M +$495K +14,227 +20%
BFM
97
Boothbay Fund Management
New York
$2.7M -$14.1K -404 -0.5%
State of Wisconsin Investment Board
98
State of Wisconsin Investment Board
Wisconsin
$2.64M +$72K +2,069 +3%
Canada Life
99
Canada Life
Manitoba, Canada
$2.6M +$331K +9,512 +14%
EAM
100
Erste Asset Management
Austria
$2.55M +$574K +16,500 +27%

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.