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Cytokinetics

430 hedge funds and large institutions have $8.86B invested in Cytokinetics in 2025 Q4 according to their latest regulatory filings, with 105 funds opening new positions, 143 increasing their positions, 134 reducing their positions, and 47 closing their positions.

New
Increased
Maintained
Reduced
Closed

306% more call options, than puts

Call options by funds: $477M | Put options by funds: $118M

123% more first-time investments, than exits

New positions opened: 105 | Existing positions closed: 47

14% more capital invested

Capital invested by funds: $7.75B → $8.86B (+$1.12B)

13% more funds holding

Funds holding: 380430 (+50)

7% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 134

3.7% less ownership

Funds ownership: 117.77%114.08% (-3.7%)

6% less funds holding in top 10

Funds holding in top 10: 1615 (-1)

Holders
430
Holders Change
+50
Holders Change %
+13.16%
% of All Funds
5.23%
Holding in Top 10
15
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-6.25%
% of All Funds
0.18%
New
105
Increased
143
Reduced
134
Closed
47
Calls
$477M
Puts
$118M
Net Calls
+$360M
Net Calls Change
+$86.1M
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
51
Sarissa Capital Management
Connecticut
$25.2M -$11.9M -192,000 -33%
GGHC
52
Gilder Gagnon Howe & Co
New York
$24.5M -$201K -3,235 -0.8%
DCM
53
DAFNA Capital Management
California
$23.6M -$1.49M -23,943 -6%
N
54
Nuveen
North Carolina
$23.5M -$102K -1,636 -0.4%
EOJOAM
55
E. Ohman J:or Asset Management
Sweden
$23.1M -$2.74M -44,075 -11%
RhumbLine Advisers
56
RhumbLine Advisers
Massachusetts
$22.7M -$1.79M -28,818 -7%
Barclays
57
Barclays
United Kingdom
$21.8M -$3.4M -54,617 -14%
ECM
58
ExodusPoint Capital Management
New York
$21.8M +$21.3M +343,144 New
GP
59
GSK plc
$21.6M +$21.2M +340,434 New
Marshall Wace
60
Marshall Wace
United Kingdom
$21.4M +$9.83M +158,051 +88%
Massachusetts Financial Services
61
Massachusetts Financial Services
Massachusetts
$20.8M -$10.5M -169,471 -34%
FTM
62
First Turn Management
California
$20.7M +$4.41M +70,873 +28%
LGM
63
Logos Global Management
California
$19.1M +$18.7M +300,000 New
Jane Street
64
Jane Street
New York
$18.1M +$17.7M +284,125 New
SPS
65
Susquehanna Portfolio Strategies
Pennsylvania
$17.7M
Two Sigma Investments
66
Two Sigma Investments
New York
$17.4M +$17M +274,017 New
CCM
67
Catalio Capital Management
New York
$16.4M -$12M -193,200 -43%
Janus Henderson Group
68
Janus Henderson Group
United Kingdom
$16.3M +$12.9M +206,648 +417%
UBS AM
69
UBS AM
Illinois
$14.9M -$207K -3,333 -1%
AQR Capital Management
70
AQR Capital Management
Connecticut
$14.8M -$17.2M -276,365 -54%
Millennium Management
71
Millennium Management
New York
$14.3M -$7.28M -117,077 -34%
Swiss National Bank
72
Swiss National Bank
Switzerland
$14.2M +$267K +4,300 +2%
Handelsbanken Fonder
73
Handelsbanken Fonder
Sweden
$13.1M -$1.79M -28,700 -12%
Invesco
74
Invesco
Georgia
$13M +$2.96M +47,629 +30%
MCP
75
Mirador Capital Partners
California
$12.6M +$74.1K +1,191 +0.6%