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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Capital International Investors
26
Capital International Investors
California
$38.6M
Morgan Stanley
27
Morgan Stanley
New York
$36.9M +$3.7M +106,335 +11%
NNPTE
28
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$35.8M +$32M +921,278 +571%
O
29
OrbiMed
New York
$35.6M -$15M -432,205 -29%
IHAM
30
Integral Health Asset Management
New York
$33M -$3.48M -100,000 -9%
Brown Advisory
31
Brown Advisory
Maryland
$32.9M -$3.17M -91,001 -8%
Aberdeen Group
32
Aberdeen Group
United Kingdom
$30.5M +$11.1M +320,508 +53%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$28.9M +$116K +3,335 +0.4%
Fisher Asset Management
34
Fisher Asset Management
Washington
$24.2M -$2.08M -59,778 -8%
Susquehanna International Group
35
Susquehanna International Group
Pennsylvania
$23.8M +$6.32M +181,704 +34%
BNP Paribas Asset Management
36
BNP Paribas Asset Management
France
$22.3M +$5.35M +153,812 +29%
CCM
37
Catalio Capital Management
New York
$19.9M +$544K +15,627 +3%
SCM
38
Sarissa Capital Management
Connecticut
$19.4M -$405K -11,643 -2%
ACM
39
ADAR1 Capital Management
Texas
$19.2M +$6.66M +191,418 +49%
FLSM
40
Frazier Life Sciences Management
California
$18.3M +$19.3M +554,731 New
TD Asset Management
41
TD Asset Management
Ontario, Canada
$18M +$3.39M +97,464 +22%
Massachusetts Financial Services
42
Massachusetts Financial Services
Massachusetts
$16.4M +$6.19M +178,069 +56%
Barclays
43
Barclays
United Kingdom
$16.3M +$6.38M +183,322 +59%
Millennium Management
44
Millennium Management
New York
$15.2M +$5.94M +170,776 +59%
American Century Companies
45
American Century Companies
Missouri
$14.3M +$2.48M +71,343 +20%
UBS AM
46
UBS AM
Illinois
$13.8M +$3.73M +107,357 +35%
EOJOAM
47
E. Ohman J:or Asset Management
Sweden
$13.4M +$2.71M +77,806 +24%
Franklin Resources
48
Franklin Resources
California
$13.3M -$4.69M -134,835 -25%
RA
49
Rosalind Advisors
Ontario, Canada
$13.2M +$13.9M +400,000 New
DCM
50
DAFNA Capital Management
California
$13.2M

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.