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Cytokinetics

355 hedge funds and large institutions have $5.58B invested in Cytokinetics in 2025 Q1 according to their latest regulatory filings, with 55 funds opening new positions, 140 increasing their positions, 110 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

302% more call options, than puts

Call options by funds: $184M | Put options by funds: $45.7M

27% more repeat investments, than reductions

Existing positions increased: 140 | Existing positions reduced: 110

25% more first-time investments, than exits

New positions opened: 55 | Existing positions closed: 44

3.79% more ownership

Funds ownership: 111.3%115.09% (+3.8%)

3% more funds holding

Funds holding: 346355 (+9)

10% less capital invested

Capital invested by funds: $6.18B → $5.58B (-$608M)

20% less funds holding in top 10

Funds holding in top 10: 1512 (-3)

Holders
355
Holders Change
+9
Holders Change %
+2.6%
% of All Funds
4.76%
Holding in Top 10
12
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-20%
% of All Funds
0.16%
New
55
Increased
140
Reduced
110
Closed
44
Calls
$184M
Puts
$45.7M
Net Calls
+$138M
Net Calls Change
+$58.6M
Name Holding Trade Value Shares
Change
Change in
Stake
HRCM
26
Hood River Capital Management
Florida
$50.5M +$12.3M +267,332 +27%
Norges Bank
27
Norges Bank
Norway
$47.3M +$8.6M +187,198 +19%
Capital International Investors
28
Capital International Investors
California
$46.9M +$3.31M +71,946 +7%
Citadel Advisors
29
Citadel Advisors
Florida
$46.2M -$10.2M -221,131 -16%
Janus Henderson Group
30
Janus Henderson Group
United Kingdom
$45.7M +$1.5M +32,729 +3%
IHAM
31
Integral Health Asset Management
New York
$44.2M +$4.6M +100,000 +10%
Brown Advisory
32
Brown Advisory
Maryland
$43.7M +$454K +9,869 +0.9%
AC
33
Armistice Capital
New York
$41.1M -$13.3M -288,610 -22%
Morgan Stanley
34
Morgan Stanley
New York
$40.7M -$11.1M -241,243 -19%
MAM
35
Melqart Asset Management
United Kingdom
$40.2M -$6.3M -136,987 -12%
RM
36
RP Management
New York
$39.4M
Bank of New York Mellon
37
Bank of New York Mellon
New York
$35M -$1.05M -22,830 -3%
PBA
38
Paradigm Biocapital Advisors
New York
$34.5M +$39.5M +858,664 New
Fisher Asset Management
39
Fisher Asset Management
Washington
$31.9M +$8.13M +176,966 +29%
Ameriprise
40
Ameriprise
Minnesota
$31.6M +$1.57M +34,182 +5%
Jane Street
41
Jane Street
New York
$30.4M +$29.8M +647,584 +599%
Jennison Associates
42
Jennison Associates
New York
$27.1M +$31M +673,932 New
Principal Financial Group
43
Principal Financial Group
Iowa
$25.3M +$16.5M +358,778 +132%
Aberdeen Group
44
Aberdeen Group
United Kingdom
$24.2M +$6.98M +151,908 +34%
SCM
45
Sarissa Capital Management
Connecticut
$24.1M -$10.7M -233,799 -28%
CCM
46
Catalio Capital Management
New York
$23.5M +$5.89M +128,225 +28%
Susquehanna International Group
47
Susquehanna International Group
Pennsylvania
$21.7M +$18.4M +399,993 +288%
Franklin Resources
48
Franklin Resources
California
$21.6M -$376K -8,189 -2%
BNP Paribas Asset Management
49
BNP Paribas Asset Management
France
$21M +$1.52M +33,106 +7%
Invesco
50
Invesco
Georgia
$20.2M -$730K -15,883 -3%

CYTK Hedge Fund Activity: Q1 2025 in Review

355 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q1 2025, worth a combined $5.58B — down 9.8% from $6.18B a quarter earlier.

Buyers outnumbered sellers: 55 funds opened new CYTK positions and 44 closed out — a net gain of 11 holders — while 140 added to existing stakes and 110 trimmed.

The largest buyer was Bank of America, adding an estimated $114M. The largest seller was Logos Global Management, exiting entirely with an estimated $42.3M sold.

  • 355 institutional investors held Cytokinetics (CYTK) as of Q1 2025, up from 346 in Q4 2024.
  • Funds reported $5.58B of Cytokinetics stock for Q1 2025, down 9.8% quarter-over-quarter.
  • 55 funds opened new Cytokinetics positions in Q1 2025 and 44 closed out, a net change of +11 holders.
  • The largest Cytokinetics buyer in Q1 2025 was Bank of America, an estimated $114M added.
  • The largest Cytokinetics seller in Q1 2025 was Logos Global Management, an estimated $42.3M sold.

Based on aggregated 13F filings for Q1 2025.