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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
ECM
326
ExodusPoint Capital Management
New York
-$3.45M -85,863 Closed
RG
327
Redmile Group
California
-$3.3M -82,098 Closed
Two Sigma Advisers
328
Two Sigma Advisers
New York
-$3.23M -80,400 Closed
M
329
Murchinson
Ontario, Canada
-$3.17M -78,795 Closed
Alyeska Investment Group
330
Alyeska Investment Group
Illinois
-$3.01M -75,000 Closed
HCA
331
Harbor Capital Advisors
Illinois
-$2.13M -53,113 Closed
CCM
332
Cinctive Capital Management
New York
-$2.1M -52,321 Closed
Two Sigma Investments
333
Two Sigma Investments
New York
-$1.77M -44,156 Closed
CM
334
CM Management
Florida
-$1.61M -40,000 Closed
Verition Fund Management
335
Verition Fund Management
Connecticut
-$1.37M -34,037 Closed
RA
336
RFG Advisory
Alabama
-$1.29M -32,005 Closed
FRM
337
Fox Run Management
Connecticut
-$932K -23,181 Closed
SMH
338
Sanders Morris Harris
Texas
-$806K -21,505 Closed
DP
339
Diadema Partners
New Jersey
-$804K -20,000 Closed
LP
340
LMR Partners
United Kingdom
-$804K -20,000 Closed
SFI
341
Susquehanna Fundamental Investments
Pennsylvania
-$779K -19,387 Closed
Simplex Trading
342
Simplex Trading
Illinois
-$624K -17,934 Closed
GCM
343
Graham Capital Management
Connecticut
-$643K -15,991 Closed
Walleye Capital
344
Walleye Capital
New York
-$491K -14,130 Closed
SC
345
SummitTX Capital
Texas
-$537K -13,357 Closed
PD
346
Point72 (DIFC)
United Arab Emirates
-$463K -11,515 Closed
QCG
347
Quadrant Capital Group
Ohio
-$443K -11,013 Closed
KAM
348
Kazazian Asset Management
Florida
-$394K -9,796 Closed
I
349
InceptionR
California
-$379K -9,433 Closed
C
350
Certuity
Florida
-$370K -9,204 Closed

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.