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Cytokinetics

311 hedge funds and large institutions have $4.55B invested in Cytokinetics in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 143 increasing their positions, 104 reducing their positions, and 71 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $216M | Put options by funds: $45.9M

38% more repeat investments, than reductions

Existing positions increased: 143 | Existing positions reduced: 104

0.19% more ownership

Funds ownership: 115.09%115.28% (+0.19%)

0% more funds holding in top 10

Funds holding in top 10: 1212 (0)

12% less funds holding

Funds holding: 355311 (-44)

18% less capital invested

Capital invested by funds: $5.58B → $4.55B (-$1.03B)

61% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 71

Holders
311
Holders Change
-44
Holders Change %
-12.39%
% of All Funds
4.09%
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.16%
New
28
Increased
143
Reduced
104
Closed
71
Calls
$216M
Puts
$45.9M
Net Calls
+$170M
Net Calls Change
+$32.6M
Name Holding Trade Value Shares
Change
Change in
Stake
AI
226
Allostery Investments
Connecticut
$165K -$2.26M -65,000 -93%
A
227
AlphaQuest
New York
$163K -$60.2K -1,731 -26%
Parallax Volatility Advisers
228
Parallax Volatility Advisers
California
$162K -$1.17M -33,673 -87%
PNC Financial Services Group
229
PNC Financial Services Group
Pennsylvania
$155K -$189K -5,445 -54%
Mirae Asset Global Investments
230
Mirae Asset Global Investments
South Korea
$152K +$23.8K +683 +17%
BG
231
Bellevue Group
Switzerland
$124K
JSAM
232
J. Safra Asset Management
New York
$122K +$20.6K +593 +19%
KBC Group
233
KBC Group
Belgium
$115K -$66.2K -1,903 -35%
CIBC Private Wealth Group
234
CIBC Private Wealth Group
Georgia
$106K +$52.7K +1,515 +89%
GFM
235
GF Fund Management
China
$99.8K
SCM
236
Sterling Capital Management
North Carolina
$94.8K +$36.3K +1,045 +57%
VIA
237
Virtus Investment Advisers
Connecticut
$93.6K -$15.2K -438 -13%
AssetMark Inc
238
AssetMark Inc
California
$87.3K +$51.5K +1,481 +128%
Lazard Asset Management
239
Lazard Asset Management
New York
$67K -$1.19M -34,113 -94%
CCM
240
Chilton Capital Management
Texas
$66.1K
CI Investments Inc
241
CI Investments Inc
Ontario, Canada
$58K -$3.41K -98 -5%
US Bancorp
242
US Bancorp
Minnesota
$57K -$23.9K -686 -28%
UB
243
UMB Bank
Missouri
$52.6K +$15.2K +437 +38%
BIG
244
Brooklyn Investment Group
New York
$49.5K +$48.6K +1,398 +1,398%
HFS
245
Hantz Financial Services
Michigan
$43K +$44K +1,264 +2,873%
DB
246
Danske Bank
Denmark
$43K +$38.3K +1,100 +550%
BC
247
BIT Capital
Germany
$41.4K +$43.6K +1,254 New
Optiver Holding
248
Optiver Holding
Netherlands
$35.2K +$8.49K +244 +30%
Jones Financial Companies
249
Jones Financial Companies
Missouri
$27.9K +$3.55K +102 +14%
Fifth Third Bancorp
250
Fifth Third Bancorp
Ohio
$26.8K -$5.95K -171 -17%

CYTK Hedge Fund Activity: Q2 2025 in Review

311 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cytokinetics (CYTK) for Q2 2025, worth a combined $4.55B — down 18% from $5.58B a quarter earlier.

Sellers outnumbered buyers: 71 funds closed out of CYTK and 28 opened new positions — a net loss of 43 holders — while 104 trimmed existing stakes and 143 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $266M. The largest seller was Marshall Wace, cutting an estimated $69.8M.

  • 311 institutional investors held Cytokinetics (CYTK) as of Q2 2025, down from 355 in Q1 2025.
  • Funds reported $4.55B of Cytokinetics stock for Q2 2025, down 18% quarter-over-quarter.
  • 28 funds opened new Cytokinetics positions in Q2 2025 and 71 closed out, a net change of -43 holders.
  • The largest Cytokinetics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $266M added.
  • The largest Cytokinetics seller in Q2 2025 was Marshall Wace, an estimated $69.8M sold.

Based on aggregated 13F filings for Q2 2025.