|
1
|
Novo Holdings A/S
Hellerup,
Denmark
|
$55M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$46M
|
-$3.61M
|
-236,666
|
-6%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$38.1M
|
–
|
–
|
–
|
|
|
4
|
OUP Management Company
Bala Cynwyd,
Pennsylvania
|
$28.1M
|
+$37.7M
|
+2,474,572
|
New
|
|
|
5
|
Avidity Partners Management
Dallas,
Texas
|
$21M
|
+$2.53M
|
+166,097
|
+10%
|
|
|
6
|
Janus Henderson Group
London,
|
$20.6M
|
-$88.4K
|
-5,803
|
-0.3%
|
|
|
7
|
Baker Bros. Advisors
New York
|
$9.24M
|
–
|
–
|
–
|
|
|
8
|
|
$6.17M
|
+$2.3M
|
+151,023
|
+39%
|
|
|
9
|
CAAS Capital Management
New York
|
$5.43M
|
-$1.56M
|
-102,236
|
-18%
|
|
|
10
|
Acuta Capital Partners
Redwood City,
California
|
$4.46M
|
–
|
–
|
–
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$3.9M
|
+$30.2K
|
+1,982
|
+0.6%
|
|
|
12
|
Ally Bridge Group
New York
|
$3.63M
|
–
|
–
|
–
|
|
|
13
|
Sofinnova Investments
Menlo Park,
California
|
$2.04M
|
-$1.02M
|
-66,871
|
-27%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$1.57M
|
+$660K
|
+43,281
|
+46%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$1.3M
|
+$349K
|
+22,917
|
+25%
|
|
|
16
|
Sphera Funds Management
Tel Aviv,
Israel
|
$1.12M
|
-$553K
|
-36,285
|
-27%
|
|
|
17
|
|
$992K
|
+$1.28M
|
+84,002
|
+2,634%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$823K
|
-$11.6K
|
-758
|
-1%
|
|
|
19
|
Millennium Management
New York
|
$590K
|
+$790K
|
+51,860
|
New
|
|
|
20
|
UBS Group
Zurich,
Switzerland
|
$394K
|
+$521K
|
+34,192
|
+8,160%
|
|
|
21
|
Renaissance Technologies
New York
|
$298K
|
+$399K
|
+26,200
|
New
|
|
|
22
|
|
$270K
|
+$361K
|
+23,713
|
New
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$259K
|
+$32.9K
|
+2,158
|
+10%
|
|
|
24
|
Gyon Technologies Capital Management
Denville,
New Jersey
|
$254K
|
+$341K
|
+22,345
|
New
|
|
|
25
|
Bank of New York Mellon
New York
|
$195K
|
+$22.8K
|
+1,499
|
+10%
|
|
