CryoPort
CYRX
172 hedge funds and large institutions have $431M invested in CryoPort in 2025 Q4 according to their latest regulatory filings, with 29 funds opening new positions, 53 increasing their positions, 56 reducing their positions, and 14 closing their positions.
685% more call options, than puts
Call options by funds: $15.2M | Put options by funds: $1.94M
107% more first-time investments, than exits
New positions opened: 29 | Existing positions closed: 14
8% more funds holding
Funds holding: 160 → 172 (+12)
3% less capital invested
Capital invested by funds: $444M → $431M (-$12.7M)
5% less repeat investments, than reductions
Existing positions increased: 53 | Existing positions reduced: 56
3.72% less ownership
Funds ownership: 93.56% → 89.84% (-3.7%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BNP Paribas Asset Management
Paris,
France
|
+$6M |
| 2 |
Millennium Management
New York
|
+$5.89M |
| 3 |
MCO
MAK Capital One
New York
|
+$3.6M |
| 4 |
First Eagle Investment Management
New York
|
+$2.95M |
| 5 |
Group One Trading
Chicago,
Illinois
|
+$2.42M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BCM
Brown Capital Management
Baltimore,
Maryland
|
-$14.3M |
| 2 |
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
-$4.05M |
| 3 |
Bank of America
Charlotte,
North Carolina
|
-$2.51M |
| 4 |
Franklin Resources
San Mateo,
California
|
-$2.08M |
| 5 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$2M |
CYRX Hedge Fund Activity: Q4 2025 in Review
172 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in CryoPort (CYRX) for Q4 2025, worth a combined $431M — down 2.9% from $444M a quarter earlier.
Buyers outnumbered sellers: 29 funds opened new CYRX positions and 14 closed out — a net gain of 15 holders — while 53 added to existing stakes and 56 trimmed.
The largest buyer was BNP Paribas Asset Management, opening a new position worth an estimated $6M. The largest seller was Brown Capital Management, cutting an estimated $14.3M.
- 172 institutional investors held CryoPort (CYRX) as of Q4 2025, up from 160 in Q3 2025.
- Funds reported $431M of CryoPort stock for Q4 2025, down 2.9% quarter-over-quarter.
- 29 funds opened new CryoPort positions in Q4 2025 and 14 closed out, a net change of +15 holders.
- The largest CryoPort buyer in Q4 2025 was BNP Paribas Asset Management, an estimated $6M added.
- The largest CryoPort seller in Q4 2025 was Brown Capital Management, an estimated $14.3M sold.
Based on aggregated 13F filings for Q4 2025.