|
1
|
BVF Inc
San Francisco,
California
|
$53.9M
|
+$45.1M
|
+3,379,561
|
+338%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$34.3M
|
+$24.3M
|
+1,816,577
|
+186%
|
|
|
3
|
Stonepine Capital Management
Bend,
Oregon
|
$13.2M
|
+$14.3M
|
+1,069,862
|
New
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$8.17M
|
+$941K
|
+70,483
|
+12%
|
|
|
5
|
BlackRock Fund Advisors
San Francisco,
California
|
$7.09M
|
+$1.97M
|
+147,586
|
+34%
|
|
|
6
|
Sio Capital Management
New York
|
$6.51M
|
+$7.07M
|
+529,226
|
New
|
|
|
7
|
BlackRock Institutional Trust
San Francisco,
California
|
$6.51M
|
+$868K
|
+65,005
|
+14%
|
|
|
8
|
DAFNA Capital Management
Los Angeles,
California
|
$3.93M
|
+$4.27M
|
+319,538
|
New
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$3.07M
|
+$336K
|
+25,164
|
+11%
|
|
|
10
|
Northern Trust
Chicago,
Illinois
|
$2.78M
|
+$696K
|
+52,121
|
+30%
|
|
|
11
|
Deerfield Management
New York
|
$2.75M
|
+$2.99M
|
+223,683
|
New
|
|
|
12
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$2.09M
|
+$792K
|
+59,345
|
+53%
|
|
|
13
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$1.86M
|
–
|
–
|
–
|
|
|
14
|
Lombard Odier Asset Management (USA)
New York
|
$1.67M
|
+$72.5K
|
+5,432
|
+4%
|
|
|
15
|
|
$1.55M
|
+$1.42M
|
+106,473
|
+538%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$1.35M
|
+$150K
|
+11,240
|
+11%
|
|
|
17
|
Alyeska Investment Group
Chicago,
Illinois
|
$923K
|
+$1M
|
+75,000
|
New
|
|
|
18
|
TIAA CREF Investment Management
New York
|
$876K
|
-$109K
|
-8,157
|
-10%
|
|
|
19
|
Bank of New York Mellon
New York
|
$843K
|
+$64.2K
|
+4,807
|
+8%
|
|
|
20
|
UBS O'Connor
Chicago,
Illinois
|
$812K
|
+$881K
|
+66,000
|
New
|
|
|
21
|
Nexthera Capital
New York
|
$807K
|
+$876K
|
+65,600
|
New
|
|
|
22
|
BlackRock Investment Management
Wilmington,
Delaware
|
$805K
|
+$112K
|
+8,422
|
+15%
|
|
|
23
|
Commerzbank Aktiengesellschaft
Frankfurt,
Germany
|
$804K
|
-$210K
|
-15,750
|
-19%
|
|
|
24
|
Sabby Management
Miami Beach,
Florida
|
$708K
|
+$769K
|
+57,567
|
New
|
|
|
25
|
Consonance Capital Management
New York
|
$635K
|
+$66.8K
|
+5,000
|
+11%
|
|
