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Castle Biosciences

180 hedge funds and large institutions have $516M invested in Castle Biosciences in 2025 Q1 according to their latest regulatory filings, with 29 funds opening new positions, 77 increasing their positions, 54 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

79% more call options, than puts

Call options by funds: $200K | Put options by funds: $112K

43% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 54

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

3.89% less ownership

Funds ownership: 94.63%90.74% (-3.9%)

9% less funds holding

Funds holding: 197180 (-17)

27% less capital invested

Capital invested by funds: $706M → $516M (-$190M)

34% less first-time investments, than exits

New positions opened: 29 | Existing positions closed: 44

Holders
180
Holders Change
-17
Holders Change %
-8.63%
% of All Funds
2.41%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
29
Increased
77
Reduced
54
Closed
44
Calls
$200K
Puts
$112K
Net Calls
+$88K
Net Calls Change
-$2.62M
Name Holding Trade Value Shares
Change
Change in
Stake
Creative Planning
126
Creative Planning
Kansas
$222K +$38.6K +1,560 +16%
Canada Life
127
Canada Life
Manitoba, Canada
$215K
Teacher Retirement System of Texas
128
Teacher Retirement System of Texas
Texas
$208K +$22.5K +908 +10%
Lido Advisors
129
Lido Advisors
California
$201K -$12.2K -493 -5%
Royal Bank of Canada
130
Royal Bank of Canada
Ontario, Canada
$182K +$4.73K +191 +2%
A
131
AlphaQuest
New York
$120K -$105K -4,223 -41%
PFSRSONJ
132
Police & Firemen's Retirement System of New Jersey
New Jersey
$117K
CUAMC
133
China Universal Asset Management Company
China
$114K -$5.45K -220 -4%
Lazard Asset Management
134
Lazard Asset Management
New York
$98K +$122K +4,928 New
KK
135
KLP Kapitalforvaltning
Norway
$96.1K
Carson Wealth (CWM LLC)
136
Carson Wealth (CWM LLC)
Nebraska
$83K +$91.6K +3,699 +835%
AssetMark Inc
137
AssetMark Inc
California
$79.7K -$10.7K -432 -10%
Amundi
138
Amundi
France
$79.4K +$102K +4,111 +15,812%
CMBA
139
C.M. Bidwell & Associates
Hawaii
$63.7K +$11.9K +482 +18%
HI
140
Harbour Investments
Wisconsin
$50K +$61.9K +2,500 New
AIP
141
Ameritas Investment Partners
Nebraska
$49K
Canada Pension Plan Investment Board
142
Canada Pension Plan Investment Board
Ontario, Canada
$48K +$37.1K +1,500 +167%
FHA
143
First Horizon Advisors
Tennessee
$36.2K -$4.95K -200 -10%
PD
144
Point72 (DIFC)
United Arab Emirates
$35.5K +$13.3K +539 +44%
C
145
Covestor
United Kingdom
$24K +$7.01K +283 +30%
Fidelity Investments
146
Fidelity Investments
Massachusetts
$23.1K +$1.86K +75 +7%
Mirae Asset Global Investments
147
Mirae Asset Global Investments
South Korea
$18.6K -$25 -1 -0.1%
AIM
148
Arcadia Investment Management
Michigan
$18.1K
AB
149
Amalgamated Bank
New York
$18K +$1.49K +60 +7%
TRCT
150
Tower Research Capital (TRC)
New York
$15.7K -$260K -10,483 -93%

CSTL Hedge Fund Activity: Q1 2025 in Review

180 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Castle Biosciences (CSTL) for Q1 2025, worth a combined $516M — down 27% from $706M a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of CSTL and 29 opened new positions — a net loss of 15 holders — while 54 trimmed existing stakes and 77 added.

The largest buyer was Schroder Investment Management Group, opening a new position worth an estimated $14.8M. The largest seller was Wasatch Advisors, cutting an estimated $19.7M.

  • 180 institutional investors held Castle Biosciences (CSTL) as of Q1 2025, down from 197 in Q4 2024.
  • Funds reported $516M of Castle Biosciences stock for Q1 2025, down 27% quarter-over-quarter.
  • 29 funds opened new Castle Biosciences positions in Q1 2025 and 44 closed out, a net change of -15 holders.
  • The largest Castle Biosciences buyer in Q1 2025 was Schroder Investment Management Group, an estimated $14.8M added.
  • The largest Castle Biosciences seller in Q1 2025 was Wasatch Advisors, an estimated $19.7M sold.

Based on aggregated 13F filings for Q1 2025.