|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$86.3M
|
+$25.4M
|
+1,488,535
|
+43%
|
|
|
2
|
Perceptive Advisors
New York
|
$59.2M
|
+$18.3M
|
+1,071,428
|
+41%
|
|
|
3
|
|
$48.2M
|
+$12.2M
|
+714,285
|
+35%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$40.8M
|
+$6.26M
|
+367,489
|
+19%
|
|
|
5
|
Vivo Capital
Palo Alto,
California
|
$40.6M
|
-$17.1M
|
-1,004,173
|
-30%
|
|
|
6
|
Versant Venture Management
San Francisco,
California
|
$35.6M
|
+$34.6M
|
+2,030,616
|
New
|
|
|
7
|
|
$31M
|
+$17.8M
|
+1,045,566
|
+145%
|
|
|
8
|
5AM Venture Management
San Francisco,
California
|
$23.9M
|
-$8.52M
|
-500,000
|
-27%
|
|
|
9
|
Eventide Asset Management
Boston,
Massachusetts
|
$23.6M
|
+$6.82M
|
+400,000
|
+42%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$18.9M
|
+$9.77M
|
+572,819
|
+113%
|
|
|
11
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$18.8M
|
+$18.3M
|
+1,071,428
|
New
|
|
|
12
|
Driehaus Capital Management
Chicago,
Illinois
|
$15.5M
|
+$15.1M
|
+886,762
|
New
|
|
|
13
|
EcoR1 Capital
San Francisco,
California
|
$15.1M
|
+$8.69M
|
+509,802
|
+146%
|
|
|
14
|
Opaleye Management
Boston,
Massachusetts
|
$7.63M
|
+$1.13M
|
+66,450
|
+18%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$7.34M
|
+$3.32M
|
+194,481
|
+87%
|
|
|
16
|
Point72 Asset Management
Stamford,
Connecticut
|
$6.92M
|
+$6.73M
|
+394,832
|
New
|
|
|
17
|
Baker Bros. Advisors
New York
|
$5.57M
|
+$2.44M
|
+142,857
|
+82%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$5.54M
|
+$3.11M
|
+182,541
|
+136%
|
|
|
19
|
Wellington Management Group
Boston,
Massachusetts
|
$5.45M
|
+$5.31M
|
+311,281
|
New
|
|
|
20
|
Burrage Capital Management
Boston,
Massachusetts
|
$4.14M
|
-$782K
|
-45,878
|
-16%
|
|
|
21
|
Novo Holdings A/S
Hellerup,
Denmark
|
$3.76M
|
+$852K
|
+50,000
|
+30%
|
|
|
22
|
|
$3.75M
|
+$3.61M
|
+211,570
|
+9,399%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$3.68M
|
+$811K
|
+47,585
|
+29%
|
|
|
24
|
Bank of New York Mellon
New York
|
$3.25M
|
+$2.55M
|
+149,591
|
+415%
|
|
|
25
|
Polar Capital
London,
United Kingdom
|
$3.07M
|
-$426K
|
-25,000
|
-13%
|
|