Cardiff Oncology
CRDF
110 hedge funds and large institutions have $76.6M invested in Cardiff Oncology in 2025 Q4 according to their latest regulatory filings, with 17 funds opening new positions, 26 increasing their positions, 33 reducing their positions, and 18 closing their positions.
632% more call options, than puts
Call options by funds: $2.08M | Put options by funds: $284K
47% more capital invested
Capital invested by funds: $52.1M → $76.6M (+$24.4M)
2.56% more ownership
Funds ownership: 37.89% → 40.45% (+2.6%)
6% less first-time investments, than exits
New positions opened: 17 | Existing positions closed: 18
2% less funds holding
Funds holding: 112 → 110 (-2)
21% less repeat investments, than reductions
Existing positions increased: 26 | Existing positions reduced: 33
Top Buyers
| 1 |
Franklin Resources
San Mateo,
California
|
+$2.8M |
| 2 |
Two Sigma Investments
New York
|
+$1.21M |
| 3 |
CS
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
+$800K |
| 4 |
Two Sigma Advisers
New York
|
+$777K |
| 5 |
GCP
GSA Capital Partners
London,
United Kingdom
|
+$490K |
Top Sellers
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
126
Optiver Holding
Amsterdam,
Netherlands
| – | -$1.03K | -498 | Closed |
|
127
Nisa Investment Advisors
St. Louis,
Missouri
| – | -$431 | -209 | Closed |
|
|
AW
128
Avion Wealth
The Woodlands,
Texas
| – | +$522 | +225 | New |
|
CRDF Hedge Fund Activity: Q4 2025 in Review
110 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Cardiff Oncology (CRDF) for Q4 2025, worth a combined $76.6M — up 47% from $52.1M a quarter earlier.
Sellers outnumbered buyers: 18 funds closed out of CRDF and 17 opened new positions — a net loss of 1 holder — while 33 trimmed existing stakes and 26 added.
The largest buyer was Franklin Resources, opening a new position worth an estimated $2.8M. The largest seller was William Blair & Company, cutting an estimated $615K.
- 110 institutional investors held Cardiff Oncology (CRDF) as of Q4 2025, down from 112 in Q3 2025.
- Funds reported $76.6M of Cardiff Oncology stock for Q4 2025, up 47% quarter-over-quarter.
- 17 funds opened new Cardiff Oncology positions in Q4 2025 and 18 closed out, a net change of -1 holder.
- The largest Cardiff Oncology buyer in Q4 2025 was Franklin Resources, an estimated $2.8M added.
- The largest Cardiff Oncology seller in Q4 2025 was William Blair & Company, an estimated $615K sold.
Based on aggregated 13F filings for Q4 2025.