Two Sigma Investments
CRDF icon

Two Sigma Investments’s Cardiff Oncology CRDF Stock Holding History

Two Sigma Investments’s Portfolio CRDF Stock Details CRDF Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$335K Sell
206,990
-517,967
-71% -$1.06M ﹤0.01% 3998
2025
Q4 		$2.04M Buy
724,957
+520,947
+255% +$1.21M ﹤0.01% 2413
2025
Q3 		$420K Sell
204,010
-239,511
-54% -$662K ﹤0.01% 3069
2025
Q2 		$1.4M Buy
443,521
+275,172
+163% +$839K ﹤0.01% 2054
2025
Q1 		$529K Buy
168,349
+63,122
+60% +$250K ﹤0.01% 2500
2024
Q4 		$457K Sell
105,227
-79,346
-43% -$248K ﹤0.01% 2575
2024
Q3 		$493K Sell
184,573
-34,056
-16% -$80.5K ﹤0.01% 2485
2024
Q2 		$485K Buy
218,629
+195,662
+852% +$737K ﹤0.01% 2387
2024
Q1 		$123K Sell
22,967
-7,700
-25% -$20.5K ﹤0.01% 2806
2023
Q4 		$45.4K Sell
30,667
-22,600
-42% -$27.3K ﹤0.01% 3004
2023
Q3 		$74K Sell
53,267
-39,965
-43% -$67.4K ﹤0.01% 2775
2023
Q2 		$137K Buy
93,232
+63,232
+211% +$102K ﹤0.01% 2710
2023
Q1 		$49.5K Buy
30,000
+6,691
+29% +$11.5K ﹤0.01% 2757
2022
Q4 		$32.6K Buy
+23,309
New +$33.4K ﹤0.01% 2641
2022
Q3 		– Sell
-12,019
Closed -$26K – 2521
2022
Q2 		$26K Sell
12,019
-454,328
-97% -$761K ﹤0.01% 2387
2022
Q1 		$1.16M Buy
466,347
+88,978
+24% +$315K ﹤0.01% 1646
2021
Q4 		$2.27M Sell
377,369
-227,381
-38% -$1.36M ﹤0.01% 1820
2021
Q3 		$4.03M Sell
604,750
-103,918
-15% -$653K 0.01% 1393
2021
Q2 		$4.71M Sell
708,668
-16,291
-2% -$138K 0.01% 1244
2021
Q1 		$6.71M Buy
724,959
+385,277
+113% +$4.68M 0.02% 896
2020
Q4 		$6.11M Buy
+339,682
New +$5.97M 0.02% 816
2018
Q4 		– Sell
-6,198
Closed -$30K – 3056
2018
Q3 		$30K Buy
+6,198
New +$29.4K ﹤0.01% 3108
2015
Q3 		– Sell
-740
Closed -$541K – 2276
2015
Q2 		$541K Buy
+740
New +$525K ﹤0.01% 2067

Other funds holding CRDF

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
LCM
Laurion Capital Management New York $2.29B AUM 75.73% 1-Year Est. Return
P
Pfizer New York $239M AUM 232.47% 1-Year Est. Return
ACA
Acorn Capital Advisors New York $352M AUM 299.18% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Franklin Resources
Franklin Resources San Mateo, California $408B AUM 30.18% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
William Blair & Company
William Blair & Company Chicago, Illinois $34.9B AUM 18.88% 1-Year Est. Return
FLPIM
F.L. Putnam Investment Management Lynnfield, Massachusetts $6.71B AUM 23.99% 1-Year Est. Return

Two Sigma Investments's CRDF Position: Q1 2026 in Review

Two Sigma Investments reduced its Cardiff Oncology (CRDF) stake by 71% in Q1 2026, selling an estimated $1.06M and leaving 206,990 shares worth $335K. The position accounts for ﹤0.01% of the portfolio, ranked #3998.

Two Sigma Investments first reported a position in CRDF in Q2 2015 and has held it in 23 quarters since. The position peaked at $6.71M in Q1 2021. 116 funds tracked by Wall St. Rank hold CRDF as of Q1 2026.

  • Two Sigma Investments held 206,990 shares of Cardiff Oncology worth $335K as of Q1 2026.
  • Two Sigma Investments sold 517,967 Cardiff Oncology shares in Q1 2026, an estimated $1.06M.
  • Cardiff Oncology made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #3998 holding.
  • Two Sigma Investments first reported a position in Cardiff Oncology in Q2 2015 and has held it in 23 quarters since.
  • Two Sigma Investments's Cardiff Oncology position peaked at $6.71M in Q1 2021.
  • 116 funds tracked by Wall St. Rank held Cardiff Oncology as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.