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Caribou Biosciences
CRBU

117 hedge funds and large institutions have $87M invested in Caribou Biosciences in 2025 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 21 increasing their positions, 47 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

68% more capital invested

Capital invested by funds: $51.9M → $87M (+$35.1M)

3.93% less ownership

Funds ownership: 43.83% → 39.9% (-3.9%)

9% less funds holding

Funds holding: 129 → 117 (-12)

38% less call options, than puts

Call options by funds: $191K | Put options by funds: $307K

43% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 28

55% less repeat investments, than reductions

Existing positions increased: 21 | Existing positions reduced: 47

Holders
117
Holders Change
-12
Holders Change %
-9.3%
% of All Funds
1.54%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
16
Increased
21
Reduced
47
Closed
28
Calls
$191K
Puts
$307K
Net Calls
-$116K
Net Calls Change
-$172K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$3.14M
2
Aberdeen Group
Aberdeen Group
United Kingdom
+$928K
3
XT
XTX Topco
Cayman Islands
+$635K
4
Bank of America
Bank of America
North Carolina
+$501K
5
Renaissance Technologies
Renaissance Technologies
New York
+$469K

Top Sellers

Rank Fund Capital Flow
1
SSA
Schonfeld Strategic Advisors
New York
-$3.24M
2
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
-$1.15M
3
AQR Capital Management
AQR Capital Management
Connecticut
-$1.11M
4
Goldman Sachs
Goldman Sachs
New York
-$1.03M
5
BlackRock
BlackRock
New York
-$801K
Name Holding Trade Value Shares
Change 		Change in
Stake
PA
76
Pinnacle Associates
New York
$30.1K – – –
PWMAG
77
Pinnacle Wealth Management Advisory Group
New Jersey
$30.1K – – –
CAGAS
78
Capital Advisory Group Advisory Services
Minnesota
$28.7K +$1.54K +814 +7%
RS
79
R Squared
Hong Kong
$28.6K +$23.2K +12,268 New
FPAS
80
Focus Partners Advisor Solutions
Missouri
$28.5K -$6.31K -3,344 -21%
Invesco
81
Invesco
Georgia
$28.4K -$23.7K -12,532 -51%
JWCA
82
J.W. Cole Advisors
Florida
$26.3K -$1.39K -735 -6%
NA
83
NewEdge Advisors
Louisiana
$24.2K – – –
LPL Financial
84
LPL Financial
California
$24K +$19.4K +10,296 New
Chevy Chase Trust
85
Chevy Chase Trust
Maryland
$23.3K – – –
MWM
86
Modern Wealth Management
Kansas
$23.3K – – –
FWM
87
FSA Wealth Management
Massachusetts
$20.1K – – –
Osaic Holdings
88
Osaic Holdings
Arizona
$18.7K +$944 +500 +6%
WANY
89
Wealthspire Advisors (New York)
New York
$17.5K +$14.2K +7,500 New
Group One Trading
90
Group One Trading
Illinois
$14.2K -$37.4K -19,831 -77%
PNC Financial Services Group
91
PNC Financial Services Group
Pennsylvania
$10.3K – – –
AUB
92
Atlantic Union Bankshares
Virginia
$7.46K +$6.04K +3,200 New
Federated Hermes
93
Federated Hermes
Pennsylvania
$7.14K -$9.16K -4,851 -61%
Carson Wealth (CWM LLC)
94
Carson Wealth (CWM LLC)
Nebraska
$6K -$59.3K -31,404 -93%
NFSG
95
Newbridge Financial Services Group
Florida
$4.66K – – –
BNP Paribas Financial Markets
96
BNP Paribas Financial Markets
France
$4.37K -$33K -17,487 -90%
Citigroup
97
Citigroup
New York
$3.66K -$56.2K -29,790 -95%
Optiver Holding
98
Optiver Holding
Netherlands
$2.57K – – –
Nisa Investment Advisors
99
Nisa Investment Advisors
Missouri
$2.39K – – –
HI
100
Harbour Investments
Wisconsin
$2.33K – – –
2 3
4
5 6

CRBU Hedge Fund Activity: Q3 2025 in Review

117 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Caribou Biosciences (CRBU) for Q3 2025, worth a combined $87M — up 68% from $51.9M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of CRBU and 16 opened new positions — a net loss of 12 holders — while 47 trimmed existing stakes and 21 added.

The largest buyer was Millennium Management, adding an estimated $3.14M. The largest seller was Schonfeld Strategic Advisors, cutting an estimated $3.24M.

  • 117 institutional investors held Caribou Biosciences (CRBU) as of Q3 2025, down from 129 in Q2 2025.
  • Funds reported $87M of Caribou Biosciences stock for Q3 2025, up 68% quarter-over-quarter.
  • 16 funds opened new Caribou Biosciences positions in Q3 2025 and 28 closed out, a net change of -12 holders.
  • The largest Caribou Biosciences buyer in Q3 2025 was Millennium Management, an estimated $3.14M added.
  • The largest Caribou Biosciences seller in Q3 2025 was Schonfeld Strategic Advisors, an estimated $3.24M sold.

Based on aggregated 13F filings for Q3 2025.