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Caribou Biosciences
CRBU

117 hedge funds and large institutions have $87M invested in Caribou Biosciences in 2025 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 21 increasing their positions, 47 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

68% more capital invested

Capital invested by funds: $51.9M → $87M (+$35.1M)

3.93% less ownership

Funds ownership: 43.83% → 39.9% (-3.9%)

9% less funds holding

Funds holding: 129 → 117 (-12)

38% less call options, than puts

Call options by funds: $191K | Put options by funds: $307K

43% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 28

55% less repeat investments, than reductions

Existing positions increased: 21 | Existing positions reduced: 47

Holders
117
Holders Change
-12
Holders Change %
-9.3%
% of All Funds
1.54%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
16
Increased
21
Reduced
47
Closed
28
Calls
$191K
Puts
$307K
Net Calls
-$116K
Net Calls Change
-$172K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$3.14M
2
Aberdeen Group
Aberdeen Group
United Kingdom
+$928K
3
XT
XTX Topco
Cayman Islands
+$635K
4
Bank of America
Bank of America
North Carolina
+$501K
5
Renaissance Technologies
Renaissance Technologies
New York
+$469K

Top Sellers

Rank Fund Capital Flow
1
SSA
Schonfeld Strategic Advisors
New York
-$3.24M
2
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
-$1.15M
3
AQR Capital Management
AQR Capital Management
Connecticut
-$1.11M
4
Goldman Sachs
Goldman Sachs
New York
-$1.03M
5
BlackRock
BlackRock
New York
-$801K
Name Holding Trade Value Shares
Change 		Change in
Stake
GAA
26
Green Alpha Advisors
Colorado
$847K -$117K -61,980 -15%
Morgan Stanley
27
Morgan Stanley
New York
$835K +$50.5K +26,738 +8%
Jacobs Levy Equity Management
28
Jacobs Levy Equity Management
New Jersey
$813K -$1.15M -607,897 -64%
UBS Group
29
UBS Group
Switzerland
$744K +$133K +70,189 +28%
DekaBank Deutsche Girozentrale
30
DekaBank Deutsche Girozentrale
Germany
$716K – – –
Point72 Asset Management
31
Point72 Asset Management
Connecticut
$672K -$2.25K -1,192 -0.4%
Citadel Advisors
32
Citadel Advisors
Florida
$618K +$47K +24,904 +10%
BC
33
Bruce & Co
Illinois
$583K – – –
Goldman Sachs
34
Goldman Sachs
New York
$570K -$1.03M -546,792 -69%
Northern Trust
35
Northern Trust
Illinois
$478K -$13.1K -6,916 -3%
MAM
36
Milestone Asset Management
Pennsylvania
$410K -$441K -233,595 -57%
BCM
37
Bridgeway Capital Management
Texas
$346K – – –
GCM
38
Graham Capital Management
Connecticut
$299K +$242K +128,352 New
Marshall Wace
39
Marshall Wace
United Kingdom
$293K +$238K +125,844 New
SL
40
Siren LLC
Connecticut
$245K – – –
CSS
41
Cubist Systematic Strategies
Connecticut
$216K -$406K -215,239 -70%
CFM
42
Catalyst Funds Management
Australia
$206K +$93.6K +49,600 +128%
Ameriprise
43
Ameriprise
Minnesota
$199K -$422K -223,601 -72%
NCM
44
Nelson Capital Management
California
$198K – – –
American Century Companies
45
American Century Companies
Missouri
$191K +$154K +81,802 New
RC
46
RBF Capital
California
$186K – – –
AQR Capital Management
47
AQR Capital Management
Connecticut
$143K -$1.11M -585,718 -91%
JFG
48
Jefferies Financial Group
New York
$110K +$89.1K +47,200 New
Commonwealth Equity Services
49
Commonwealth Equity Services
Massachusetts
$109K -$24.6K -13,031 -22%
Qube Research & Technologies (QRT)
50
Qube Research & Technologies (QRT)
United Kingdom
$105K +$85.2K +45,150 New
1
2
3 4 5

CRBU Hedge Fund Activity: Q3 2025 in Review

117 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Caribou Biosciences (CRBU) for Q3 2025, worth a combined $87M — up 68% from $51.9M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of CRBU and 16 opened new positions — a net loss of 12 holders — while 47 trimmed existing stakes and 21 added.

The largest buyer was Millennium Management, adding an estimated $3.14M. The largest seller was Schonfeld Strategic Advisors, cutting an estimated $3.24M.

  • 117 institutional investors held Caribou Biosciences (CRBU) as of Q3 2025, down from 129 in Q2 2025.
  • Funds reported $87M of Caribou Biosciences stock for Q3 2025, up 68% quarter-over-quarter.
  • 16 funds opened new Caribou Biosciences positions in Q3 2025 and 28 closed out, a net change of -12 holders.
  • The largest Caribou Biosciences buyer in Q3 2025 was Millennium Management, an estimated $3.14M added.
  • The largest Caribou Biosciences seller in Q3 2025 was Schonfeld Strategic Advisors, an estimated $3.24M sold.

Based on aggregated 13F filings for Q3 2025.