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CNTB

Connect Biopharma Holdings

29 hedge funds and large institutions have $23.9M invested in Connect Biopharma Holdings in 2025 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 5 increasing their positions, 4 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed

17,033% more call options, than puts

Call options by funds: $514K | Put options by funds: $3K

876% more capital invested

Capital invested by funds: $2.45M → $23.9M (+$21.4M)

650% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 2

81% more funds holding

Funds holding: 1629 (+13)

25% more repeat investments, than reductions

Existing positions increased: 5 | Existing positions reduced: 4

12.23% more ownership

Funds ownership: 2.91%15.14% (+12%)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
29
Holders Change
+13
Holders Change %
+81.25%
% of All Funds
0.35%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
15
Increased
5
Reduced
4
Closed
2
Calls
$514K
Puts
$3K
Net Calls
+$511K
Net Calls Change
+$510K
Name Holding Trade Value Shares
Change
Change in
Stake
IC
1
Ikarian Capital
Texas
$13.5M +$10.2M +4,788,486 New
BFM
2
Boothbay Fund Management
New York
$3.48M +$2.63M +1,234,582 New
PA
3
Perceptive Advisors
New York
$2.24M +$1.69M +792,696 New
BCM
4
BML Capital Management
Indiana
$1.15M -$1.83M -858,613 -68%
DMKJ
5
David M. Knott Jr
$564K +$427K +200,000 New
RB
6
Richmond Brothers
Michigan
$489K +$370K +173,485 New
Renaissance Technologies
7
Renaissance Technologies
New York
$404K -$32.2K -15,100 -10%
Marshall Wace
8
Marshall Wace
United Kingdom
$362K +$150K +70,337 +121%
Citadel Advisors
9
Citadel Advisors
Florida
$281K +$212K +99,493 New
Jane Street
10
Jane Street
New York
$232K +$175K +82,226 New
OAC
11
OMERS Administration Corp
Ontario, Canada
$228K +$172K +80,808 New
Susquehanna International Group
12
Susquehanna International Group
Pennsylvania
$202K +$123K +57,755 +420%
KWM
13
Koa Wealth Management
California
$140K
Millennium Management
14
Millennium Management
New York
$133K +$100K +47,050 New
Royal Bank of Canada
15
Royal Bank of Canada
Ontario, Canada
$114K +$86.2K +40,400 New
PAP
16
Persistent Asset Partners
Hong Kong
$75.5K +$57.1K +26,774 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$65.8K
HF
18
HRT Financial
New York
$47K +$13.5K +6,328 +61%
Point72 Asset Management
19
Point72 Asset Management
Connecticut
$46.5K +$35.2K +16,503 New
SP
20
SmartHarvest Portfolios
Washington
$36.4K +$27.5K +12,897 New
MWA
21
Monograph Wealth Advisors
California
$31.4K
Qube Research & Technologies (QRT)
22
Qube Research & Technologies (QRT)
United Kingdom
$29.5K +$22.3K +10,449 New
UBS Group
23
UBS Group
Switzerland
$8.93K +$6.32K +2,964 +1,475%
Morgan Stanley
24
Morgan Stanley
New York
$6.23K +$4.5K +2,109 +2,109%
EWA
25
EverSource Wealth Advisors
Alabama
$3.63K -$627 -294 -19%

CNTB Hedge Fund Activity: Q4 2025 in Review

29 of the 8,228 institutional investors tracked by Wall St. Rank reported a position in Connect Biopharma Holdings (CNTB) for Q4 2025, worth a combined $23.9M — up 876% from $2.45M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new CNTB positions and 2 closed out — a net gain of 13 holders — while 5 added to existing stakes and 4 trimmed.

The largest buyer was Ikarian Capital, opening a new position worth an estimated $10.2M. The largest seller was BML Capital Management, cutting an estimated $1.83M.

  • 29 institutional investors held Connect Biopharma Holdings (CNTB) as of Q4 2025, up from 16 in Q3 2025.
  • Funds reported $23.9M of Connect Biopharma Holdings stock for Q4 2025, up 876% quarter-over-quarter.
  • 15 funds opened new Connect Biopharma Holdings positions in Q4 2025 and 2 closed out, a net change of +13 holders.
  • The largest Connect Biopharma Holdings buyer in Q4 2025 was Ikarian Capital, an estimated $10.2M added.
  • The largest Connect Biopharma Holdings seller in Q4 2025 was BML Capital Management, an estimated $1.83M sold.

Based on aggregated 13F filings for Q4 2025.