|
1
|
|
$18.8M
|
+$28.2M
|
+4,677,938
|
New
|
|
|
2
|
TRV GP
Boston,
Massachusetts
|
$12.2M
|
–
|
–
|
–
|
|
|
3
|
|
$6.24M
|
+$1.46M
|
+242,255
|
+18%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$6.13M
|
-$266K
|
-44,100
|
-3%
|
|
|
5
|
Cormorant Asset Management
Boston,
Massachusetts
|
$5.1M
|
–
|
–
|
–
|
|
|
6
|
|
$3.35M
|
–
|
–
|
–
|
|
|
7
|
VHCP Management II
New York
|
$2.91M
|
–
|
–
|
–
|
|
|
8
|
Deerfield Management
New York
|
$2.55M
|
–
|
–
|
–
|
|
|
9
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$1.27M
|
–
|
–
|
–
|
|
|
10
|
Baker Bros. Advisors
New York
|
$535K
|
–
|
–
|
–
|
|
|
11
|
First Eagle Investment Management
New York
|
$501K
|
+$754K
|
+125,000
|
New
|
|
|
12
|
|
$427K
|
-$502K
|
-83,179
|
-44%
|
|
|
13
|
EcoR1 Capital
San Francisco,
California
|
$318K
|
-$1.21M
|
-200,806
|
-72%
|
|
|
14
|
Sphera Funds Management
Tel Aviv,
Israel
|
$281K
|
+$423K
|
+70,162
|
New
|
|
|
15
|
VHCP Management III
New York
|
$267K
|
–
|
–
|
–
|
|
|
16
|
Jasper Ridge Partners
Menlo Park,
California
|
$247K
|
+$372K
|
+61,643
|
New
|
|
|
17
|
Vanguard Group
Malvern,
Pennsylvania
|
$240K
|
-$525K
|
-87,054
|
-59%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$204K
|
+$33.9K
|
+5,624
|
+12%
|
|
|
19
|
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
$108K
|
+$162K
|
+26,919
|
New
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$68K
|
+$102K
|
+16,894
|
New
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$55K
|
+$12K
|
+1,987
|
+17%
|
|
|
22
|
|
$36K
|
+$898
|
+149
|
+2%
|
|
|
23
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
$24K
|
–
|
–
|
–
|
|
|
24
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$21K
|
-$28.7K
|
-4,768
|
-47%
|
|
|
25
|
Bank of America
Charlotte,
North Carolina
|
$17K
|
+$19.9K
|
+3,298
|
+325%
|
|
