|
1
|
Novo Holdings A/S
Hellerup,
Denmark
|
$115M
|
–
|
–
|
–
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$84.8M
|
-$5.51M
|
-155,840
|
-6%
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$48M
|
+$18.9M
|
+535,331
|
+68%
|
|
|
4
|
Citadel Advisors
Miami,
Florida
|
$25.6M
|
+$22.2M
|
+626,751
|
+807%
|
|
|
5
|
Perceptive Advisors
New York
|
$23.3M
|
+$3.16M
|
+89,334
|
+16%
|
|
|
6
|
Marshall Wace
London,
United Kingdom
|
$17.7M
|
+$10.8M
|
+306,344
|
+171%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$17.6M
|
-$9.87M
|
-278,965
|
-37%
|
|
|
8
|
Great Point Partners
Greenwich,
Connecticut
|
$15.9M
|
+$1.34M
|
+37,865
|
+9%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$13.5M
|
+$3.95M
|
+111,726
|
+43%
|
|
|
10
|
Sphera Funds Management
Tel Aviv,
Israel
|
$13M
|
-$1.49M
|
-42,000
|
-11%
|
|
|
11
|
Adage Capital Partners
Boston,
Massachusetts
|
$10.9M
|
–
|
–
|
–
|
|
|
12
|
AWM Investment Company
New York
|
$10.5M
|
–
|
–
|
–
|
|
|
13
|
BlackRock Fund Advisors
San Francisco,
California
|
$10.1M
|
+$9.47M
|
+267,629
|
+3,125%
|
|
|
14
|
Vivo Capital
Palo Alto,
California
|
$8.19M
|
–
|
–
|
–
|
|
|
15
|
Balyasny Asset Management
Chicago,
Illinois
|
$6.7M
|
+$2.71M
|
+76,500
|
+71%
|
|
|
16
|
BlackRock Institutional Trust
San Francisco,
California
|
$6.25M
|
+$2.9M
|
+82,007
|
+91%
|
|
|
17
|
VHCP Management II
New York
|
$5.79M
|
–
|
–
|
–
|
|
|
18
|
EAM Investors
Solana Beach,
California
|
$5.59M
|
-$3.08M
|
-86,921
|
-36%
|
|
|
19
|
Credit Suisse
Zurich,
Switzerland
|
$5.54M
|
+$5.39M
|
+152,295
|
New
|
|
|
20
|
Point72 Asset Management
Stamford,
Connecticut
|
$5.09M
|
+$1.67M
|
+47,116
|
+51%
|
|
|
21
|
|
$4.71M
|
+$1.82M
|
+51,324
|
+66%
|
|
|
22
|
Bogle Investment Management
Newton Lower Falls,
Massachusetts
|
$4.5M
|
+$4.37M
|
+123,503
|
New
|
|
|
23
|
|
$3.79M
|
+$3.68M
|
+104,107
|
New
|
|
|
24
|
Chartwell Investment Partners
Berywn,
Pennsylvania
|
$3.03M
|
-$5.08M
|
-143,715
|
-63%
|
|
|
25
|
PointState Capital
New York
|
$2.8M
|
-$96.7K
|
-2,732
|
-3%
|
|
