|
1
|
Third Rock Ventures
Boston,
Massachusetts
|
$43.2M
|
–
|
–
|
–
|
|
|
2
|
Flagship Ventures 2007 General Partner
Cambridge,
Massachusetts
|
$17M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$15.7M
|
–
|
–
|
–
|
|
|
4
|
Broadfin Capital
New York
|
$8.62M
|
-$6.12K
|
-28
|
-0.1%
|
|
|
5
|
Franklin Resources
San Mateo,
California
|
$8.29M
|
+$1.31M
|
+5,985
|
+15%
|
|
|
6
|
Royce & Associates
New York
|
$3.47M
|
+$4.25M
|
+19,430
|
New
|
|
|
7
|
|
$2.66M
|
-$728K
|
-3,334
|
-18%
|
|
|
8
|
Redmile Group
San Francisco,
California
|
$2.14M
|
–
|
–
|
–
|
|
|
9
|
Ascend Capital
Orinda,
California
|
$1.87M
|
+$2.29M
|
+10,500
|
New
|
|
|
10
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.75M
|
-$4.53M
|
-20,712
|
-68%
|
|
|
11
|
EverPoint Asset Management
Stamford,
Connecticut
|
$1.56M
|
+$1.91M
|
+8,750
|
New
|
|
|
12
|
Point72 Asset Management
Stamford,
Connecticut
|
$1.55M
|
–
|
–
|
–
|
|
|
13
|
C WorldWide Group
Copenhagen,
Denmark
|
$1.49M
|
+$1.09M
|
+5,000
|
+148%
|
|
|
14
|
BlackRock Fund Advisors
San Francisco,
California
|
$1.03M
|
-$1.97K
|
-9
|
-0.2%
|
|
|
15
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$1M
|
–
|
–
|
–
|
|
|
16
|
Vanguard Group
Malvern,
Pennsylvania
|
$908K
|
+$73.6K
|
+337
|
+7%
|
|
|
17
|
Principal Financial Group
Des Moines,
Iowa
|
$878K
|
+$9.83K
|
+45
|
+0.9%
|
|
|
18
|
Sphera Funds Management
Tel Aviv,
Israel
|
$777K
|
–
|
–
|
–
|
|
|
19
|
State of New Jersey Common Pension Fund D
Trenton,
New Jersey
|
$669K
|
–
|
–
|
–
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$612K
|
+$2.62K
|
+12
|
+0.4%
|
|
|
21
|
Bank of New York Mellon
New York
|
$468K
|
+$35.2K
|
+161
|
+7%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$437K
|
+$15.1K
|
+69
|
+3%
|
|
|
23
|
Sarissa Capital Management
Greenwich,
Connecticut
|
$368K
|
–
|
–
|
–
|
|
|
24
|
BlackRock Institutional Trust
San Francisco,
California
|
$359K
|
+$47.2K
|
+216
|
+12%
|
|
|
25
|
TCW Group
Los Angeles,
California
|
$355K
|
-$36K
|
-165
|
-8%
|
|
