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Cabaletta Bio

95 hedge funds and large institutions have $167M invested in Cabaletta Bio in 2025 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 33 increasing their positions, 18 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,725% more call options, than puts

Call options by funds: $5.09M | Put options by funds: $279K

275% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 8

83% more repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 18

27% more funds holding

Funds holding: 7595 (+20)

3.53% more ownership

Funds ownership: 75.67%79.2% (+3.5%)

3% more capital invested

Capital invested by funds: $162M → $167M (+$4.96M)

Holders
95
Holders Change
+20
Holders Change %
+26.67%
% of All Funds
1.15%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
30
Increased
33
Reduced
18
Closed
8
Calls
$5.09M
Puts
$279K
Net Calls
+$4.81M
Net Calls Change
-$353K
Name Holding Trade Value Shares
Change
Change in
Stake
QC
51
Quadrature Capital
United Kingdom
$145K +$58.1K +23,465 +55%
American Century Companies
52
American Century Companies
Missouri
$129K +$116K +46,745 +389%
Point72 Asset Management
53
Point72 Asset Management
Connecticut
$124K +$140K +56,648 New
M
54
MATAURO
New York
$121K +$137K +55,108 New
Bank of New York Mellon
55
Bank of New York Mellon
New York
$118K +$15.5K +6,237 +13%
Balyasny Asset Management
56
Balyasny Asset Management
Illinois
$113K +$128K +51,552 New
Charles Schwab
57
Charles Schwab
California
$111K
JFG
58
Jefferies Financial Group
New York
$98.8K -$5.88K -2,375 -5%
LPL Financial
59
LPL Financial
California
$93.3K +$106K +42,615 New
LIP
60
Lighthouse Investment Partners
Florida
$85.1K +$96.3K +38,880 New
Citadel Advisors
61
Citadel Advisors
Florida
$73.4K -$1.67M -671,963 -95%
SG Americas Securities
62
SG Americas Securities
New York
$67K +$23.2K +9,365 +44%
TRCT
63
Tower Research Capital (TRC)
New York
$66.5K +$64.4K +25,978 +595%
FAM
64
Fred Alger Management
New York
$61.4K -$78.8K -31,792 -53%
Mercer Global Advisors
65
Mercer Global Advisors
Colorado
$58.1K +$65.7K +26,510 New
CFO
66
Callan Family Office
Pennsylvania
$49.4K +$55.9K +22,575 New
VPIM
67
Vanguard Personalized Indexing Management
California
$49K +$577 +233 +1%
Jones Financial Companies
68
Jones Financial Companies
Missouri
$45.2K +$1.62K +653 +3%
CHAM
69
Clear Harbor Asset Management
Connecticut
$42.7K +$48.3K +19,500 New
AP
70
Antipodes Partners
Australia
$37.6K +$42.6K +17,187 New
CUAMC
71
China Universal Asset Management Company
China
$34.4K +$38.9K +15,686 New
CFS
72
CRA Financial Services
New Jersey
$32.9K
PAG
73
Private Advisor Group
New Jersey
$32.2K +$36.5K +14,725 New
Bank of America
74
Bank of America
North Carolina
$31.5K -$629K -253,666 -95%
Fidelity Investments
75
Fidelity Investments
Massachusetts
$28.6K -$2.52K -1,019 -7%

CABA Hedge Fund Activity: Q4 2025 in Review

95 of the 8,245 institutional investors tracked by Wall St. Rank reported a position in Cabaletta Bio (CABA) for Q4 2025, worth a combined $167M — up 3.1% from $162M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new CABA positions and 8 closed out — a net gain of 22 holders — while 33 added to existing stakes and 18 trimmed.

The largest buyer was Millennium Management, adding an estimated $5.08M. The largest seller was Heights Capital Management, exiting entirely with an estimated $4.88M sold.

  • 95 institutional investors held Cabaletta Bio (CABA) as of Q4 2025, up from 75 in Q3 2025.
  • Funds reported $167M of Cabaletta Bio stock for Q4 2025, up 3.1% quarter-over-quarter.
  • 30 funds opened new Cabaletta Bio positions in Q4 2025 and 8 closed out, a net change of +22 holders.
  • The largest Cabaletta Bio buyer in Q4 2025 was Millennium Management, an estimated $5.08M added.
  • The largest Cabaletta Bio seller in Q4 2025 was Heights Capital Management, an estimated $4.88M sold.

Based on aggregated 13F filings for Q4 2025.