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Cabaletta Bio
CABA

95 hedge funds and large institutions have $167M invested in Cabaletta Bio in 2025 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 33 increasing their positions, 18 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,725% more call options, than puts

Call options by funds: $5.09M | Put options by funds: $279K

275% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 8

83% more repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 18

27% more funds holding

Funds holding: 75 → 95 (+20)

3.53% more ownership

Funds ownership: 75.67% → 79.2% (+3.5%)

3% more capital invested

Capital invested by funds: $162M → $167M (+$4.96M)

Holders
95
Holders Change
+20
Holders Change %
+26.67%
% of All Funds
1.15%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
30
Increased
33
Reduced
18
Closed
8
Calls
$5.09M
Puts
$279K
Net Calls
+$4.81M
Net Calls Change
-$353K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$5.08M
2
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$3.71M
3
Two Sigma Investments
Two Sigma Investments
New York
+$3.39M
4
IC
Ikarian Capital
Texas
+$2.23M
5
Schroder Investment Management Group
Schroder Investment Management Group
United Kingdom
+$1.88M

Top Sellers

Rank Fund Capital Flow
1
HCM
Heights Capital Management
California
-$4.88M
2
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$3.04M
3
WP
Woodline Partners
California
-$2.19M
4
Citadel Advisors
Citadel Advisors
Florida
-$1.67M
5
CAM
Cormorant Asset Management
Massachusetts
-$1.49M
Name Holding Trade Value Shares
Change 		Change in
Stake
Dimensional Fund Advisors
26
Dimensional Fund Advisors
Texas
$990K +$1.12M +452,039 New
RBI
27
Raiffeisen Bank International
Austria
$968K +$248K +100,000 +29%
Goldman Sachs
28
Goldman Sachs
New York
$943K +$392K +158,078 +58%
State Street
29
State Street
Massachusetts
$932K +$121K +48,678 +13%
UBS Group
30
UBS Group
Switzerland
$910K +$26.2K +10,557 +3%
6CM
31
683 Capital Management
New York
$851K +$963K +388,562 New
AC
32
Almitas Capital
California
$849K – – –
Qube Research & Technologies (QRT)
33
Qube Research & Technologies (QRT)
United Kingdom
$725K +$600K +242,068 +272%
GCP
34
GSA Capital Partners
United Kingdom
$666K +$753K +303,992 New
BFM
35
Boothbay Fund Management
New York
$533K +$603K +243,445 New
Northern Trust
36
Northern Trust
Illinois
$522K +$28.4K +11,455 +5%
Barclays
37
Barclays
United Kingdom
$483K +$539K +217,613 +7,058%
Invesco
38
Invesco
Georgia
$414K +$165K +66,395 +54%
SCM
39
Stonepine Capital Management
Oregon
$375K +$424K +171,100 New
XT
40
XTX Topco
Cayman Islands
$340K -$319K -128,912 -45%
GCM
41
Graham Capital Management
Connecticut
$332K +$375K +151,451 New
Squarepoint
42
Squarepoint
New York
$327K +$340K +137,226 +1,156%
Hudson Bay Capital Management
43
Hudson Bay Capital Management
Connecticut
$304K +$344K +138,729 New
Susquehanna International Group
44
Susquehanna International Group
Pennsylvania
$303K -$579K -233,827 -63%
BCM
45
Bridgeway Capital Management
Texas
$286K +$86.7K +35,000 +37%
OAC
46
OMERS Administration Corp
Ontario, Canada
$209K +$236K +95,400 New
LBA
47
Letko, Brosseau & Associates
Quebec, Canada
$198K +$224K +90,475 New
TD Asset Management
48
TD Asset Management
Ontario, Canada
$194K – – –
Citigroup
49
Citigroup
New York
$162K +$182K +73,422 +20,859%
DTL
50
Dynamic Technology Lab
Singapore
$146K +$166K +66,789 New
1
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CABA Hedge Fund Activity: Q4 2025 in Review

95 of the 8,245 institutional investors tracked by Wall St. Rank reported a position in Cabaletta Bio (CABA) for Q4 2025, worth a combined $167M — up 3.1% from $162M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new CABA positions and 8 closed out — a net gain of 22 holders — while 33 added to existing stakes and 18 trimmed.

The largest buyer was Millennium Management, adding an estimated $5.08M. The largest seller was Heights Capital Management, exiting entirely with an estimated $4.88M sold.

  • 95 institutional investors held Cabaletta Bio (CABA) as of Q4 2025, up from 75 in Q3 2025.
  • Funds reported $167M of Cabaletta Bio stock for Q4 2025, up 3.1% quarter-over-quarter.
  • 30 funds opened new Cabaletta Bio positions in Q4 2025 and 8 closed out, a net change of +22 holders.
  • The largest Cabaletta Bio buyer in Q4 2025 was Millennium Management, an estimated $5.08M added.
  • The largest Cabaletta Bio seller in Q4 2025 was Heights Capital Management, an estimated $4.88M sold.

Based on aggregated 13F filings for Q4 2025.