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Cabaletta Bio
CABA

86 hedge funds and large institutions have $111M invested in Cabaletta Bio in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 23 increasing their positions, 28 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,087% more call options, than puts

Call options by funds: $1.8M | Put options by funds: $152K

120% more capital invested

Capital invested by funds: $50.3M → $111M (+$60.3M)

69.13% more ownership

Funds ownership: 74.27% → 143.4% (+69%)

7% less funds holding

Funds holding: 92 → 86 (-6)

18% less repeat investments, than reductions

Existing positions increased: 23 | Existing positions reduced: 28

19% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 32

Holders
86
Holders Change
-6
Holders Change %
-6.52%
% of All Funds
1.13%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
26
Increased
23
Reduced
28
Closed
32
Calls
$1.8M
Puts
$152K
Net Calls
+$1.65M
Net Calls Change
+$1.5M

Top Buyers

Rank Fund Capital Flow
1
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$10.8M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$8.1M
3
CAM
Cormorant Asset Management
Massachusetts
+$7.8M
4
Alyeska Investment Group
Alyeska Investment Group
Illinois
+$7.49M
5
Jennison Associates
Jennison Associates
New York
+$5.59M

Top Sellers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
-$3.87M
2
CF
Cantor Fitzgerald
New York
-$1.48M
3
IHAM
Integral Health Asset Management
New York
-$1.18M
4
State Street
State Street
Massachusetts
-$1.12M
5
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$1.04M
Name Holding Trade Value Shares
Change 		Change in
Stake
AC
26
Almitas Capital
California
$559K – – –
Goldman Sachs
27
Goldman Sachs
New York
$537K +$35.5K +22,766 +7%
RBI
28
Raiffeisen Bank International
Austria
$531K – – –
Federated Hermes
29
Federated Hermes
Pennsylvania
$524K +$1.76K +1,129 +0.3%
Prudential Financial
30
Prudential Financial
New Jersey
$432K -$5.44K -3,490 -1%
Axa
31
Axa
France
$411K +$685 +439 +0.2%
Two Sigma Investments
32
Two Sigma Investments
New York
$384K -$108K -69,054 -21%
Jane Street
33
Jane Street
New York
$362K +$372K +238,325 New
CSS
34
Cubist Systematic Strategies
Connecticut
$358K +$367K +235,270 New
State Street
35
State Street
Massachusetts
$331K -$1.12M -720,751 -77%
Marshall Wace
36
Marshall Wace
United Kingdom
$290K +$246K +157,497 +471%
Northern Trust
37
Northern Trust
Illinois
$202K -$416K -266,746 -67%
Renaissance Technologies
38
Renaissance Technologies
New York
$192K +$180K +115,200 +1,057%
HF
39
HRT Financial
New York
$189K +$194K +124,395 New
Susquehanna International Group
40
Susquehanna International Group
Pennsylvania
$188K +$103K +65,845 +114%
XT
41
XTX Topco
Cayman Islands
$148K +$152K +97,260 New
Thrivent Financial for Lutherans
42
Thrivent Financial for Lutherans
Minnesota
$145K – – –
TD Asset Management
43
TD Asset Management
Ontario, Canada
$135K – – –
TCM
44
TCG Crossover Management
California
$132K – – –
Invesco
45
Invesco
Georgia
$129K +$36.1K +23,156 +38%
JP Morgan Chase
46
JP Morgan Chase
New York
$123K -$266K -170,641 -68%
Squarepoint
47
Squarepoint
New York
$109K +$111K +71,441 New
Citigroup
48
Citigroup
New York
$95K +$48.4K +31,037 +99%
FAM
49
Fred Alger Management
New York
$90.9K -$651K -417,397 -87%
JG
50
Jain Global
New York
$85.4K +$87.6K +56,160 New
1
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CABA Hedge Fund Activity: Q2 2025 in Review

86 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cabaletta Bio (CABA) for Q2 2025, worth a combined $111M — up 120% from $50.3M a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of CABA and 26 opened new positions — a net loss of 6 holders — while 28 trimmed existing stakes and 23 added.

The largest buyer was Bain Capital Life Sciences Investors, adding an estimated $10.8M. The largest seller was BlackRock, cutting an estimated $3.87M.

  • 86 institutional investors held Cabaletta Bio (CABA) as of Q2 2025, down from 92 in Q1 2025.
  • Funds reported $111M of Cabaletta Bio stock for Q2 2025, up 120% quarter-over-quarter.
  • 26 funds opened new Cabaletta Bio positions in Q2 2025 and 32 closed out, a net change of -6 holders.
  • The largest Cabaletta Bio buyer in Q2 2025 was Bain Capital Life Sciences Investors, an estimated $10.8M added.
  • The largest Cabaletta Bio seller in Q2 2025 was BlackRock, an estimated $3.87M sold.

Based on aggregated 13F filings for Q2 2025.