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BLTE

Belite Bio
BLTE

69 hedge funds and large institutions have $1.15B invested in Belite Bio in 2025 Q4 according to their latest regulatory filings, with 40 funds opening new positions, 17 increasing their positions, 10 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

900% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 4

581% more capital invested

Capital invested by funds: $169M → $1.15B (+$984M)

103% more funds holding

Funds holding: 34 → 69 (+35)

70% more repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 10

11.98% more ownership

Funds ownership: 7.19% → 19.17% (+12%)

Holders
69
Holders Change
+35
Holders Change %
+102.94%
% of All Funds
0.84%
Holding in Top 10
3
Holding in Top 10 Change
+3
Holding in Top 10 Change %
% of All Funds
0.04%
New
40
Increased
17
Reduced
10
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
DGM
Darwin Global Management
Jersey
+$359M
2
Millennium Management
Millennium Management
New York
+$63.7M
3
RI
RTW Investments
New York
+$47.7M
4
PA
Perceptive Advisors
New York
+$43.2M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
+$33.3M

Top Sellers

1
RCM
RA Capital Management
Massachusetts
-$52.4M
2
VPC
Vestal Point Capital
New York
-$23.1M
3
SCM
Soleus Capital Management
Connecticut
-$20.1M
4
JP Morgan Chase
JP Morgan Chase
New York
-$1.16M
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
-$1.08M
Name Holding Trade Value Shares
Change 		Change in
Stake
DGM
1
Darwin Global Management
Jersey
$487M +$359M +3,027,704 New
RI
2
RTW Investments
New York
$114M +$47.7M +402,832 +129%
Millennium Management
3
Millennium Management
New York
$89.4M +$63.7M +538,141 +2,595%
RCM
4
RA Capital Management
Massachusetts
$69.2M -$52.4M -442,516 -51%
PA
5
Perceptive Advisors
New York
$66.3M +$43.2M +364,451 +732%
EAM
6
Eventide Asset Management
Massachusetts
$61.3M +$22.2M +187,779 +96%
Point72 Asset Management
7
Point72 Asset Management
Connecticut
$45.5M +$33.3M +281,337 +9,075%
DM
8
Deerfield Management
New York
$37.4M +$27.7M +233,813 New
Marshall Wace
9
Marshall Wace
United Kingdom
$30.8M +$616K +5,200 +3%
UBS Group
10
UBS Group
Switzerland
$20.6M +$13.9M +117,418 +1,036%
MB
11
MPM BioImpact
Massachusetts
$14M +$10.4M +87,760 New
Holocene Advisors
12
Holocene Advisors
New York
$13.4M +$9.96M +84,067 New
FAM
13
Fred Alger Management
New York
$12.7M +$9.4M +79,394 New
WSL
14
Western Standard LLC
California
$9.6M +$7.11M +60,026 New
Goldman Sachs
15
Goldman Sachs
New York
$7.13M +$4.84M +40,893 +1,103%
SCM
16
Soleus Capital Management
Connecticut
$6.46M -$20.1M -169,646 -81%
ACM
17
ADAR1 Capital Management
Texas
$6.37M +$4.72M +39,839 New
Jane Street
18
Jane Street
New York
$5.17M +$3.83M +32,318 New
Morgan Stanley
19
Morgan Stanley
New York
$4.48M +$2.7M +22,783 +436%
SCM
20
Squadron Capital Management
Illinois
$4.16M +$3.08M +26,000 New
QC
21
Quadrature Capital
United Kingdom
$3.97M +$2.49M +21,002 +548%
SCM
22
Superstring Capital Management
New York
$3.95M +$2.93M +24,703 New
AAA
23
Affinity Asset Advisors
New York
$3.2M +$2.37M +20,000 New
PHS
24
PFM Health Sciences
California
$3.17M +$2.35M +19,823 New
WP
25
Woodline Partners
California
$2.89M +$2.14M +18,041 New
1
2 3

BLTE Hedge Fund Activity: Q4 2025 in Review

69 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Belite Bio (BLTE) for Q4 2025, worth a combined $1.15B — up 581% from $169M a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new BLTE positions and 4 closed out — a net gain of 36 holders — while 17 added to existing stakes and 10 trimmed.

The largest buyer was Darwin Global Management, opening a new position worth an estimated $359M. The largest seller was RA Capital Management, cutting an estimated $52.4M.

  • 69 institutional investors held Belite Bio (BLTE) as of Q4 2025, up from 34 in Q3 2025.
  • Funds reported $1.15B of Belite Bio stock for Q4 2025, up 581% quarter-over-quarter.
  • 40 funds opened new Belite Bio positions in Q4 2025 and 4 closed out, a net change of +36 holders.
  • The largest Belite Bio buyer in Q4 2025 was Darwin Global Management, an estimated $359M added.
  • The largest Belite Bio seller in Q4 2025 was RA Capital Management, an estimated $52.4M sold.

Based on aggregated 13F filings for Q4 2025.