|
1
|
RA Capital Management
Boston,
Massachusetts
|
$61.2M
|
+$56.4M
|
+2,448,350
|
New
|
|
|
2
|
VHCP Management II
New York
|
$37.9M
|
+$38.3M
|
+1,664,300
|
New
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$25.9M
|
+$23.8M
|
+1,035,523
|
New
|
|
|
4
|
|
$25.5M
|
+$23.5M
|
+1,020,932
|
New
|
|
|
5
|
Knoll Capital Management
Miami,
Florida
|
$20.2M
|
+$18.6M
|
+807,224
|
New
|
|
|
6
|
Janus Henderson Group
London,
|
$16.1M
|
+$14.9M
|
+645,743
|
New
|
|
|
7
|
|
$14.8M
|
+$13.7M
|
+593,225
|
New
|
|
|
8
|
Emerald Advisers
Leola,
Pennsylvania
|
$12.4M
|
+$11.5M
|
+497,880
|
New
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$12.4M
|
+$11.4M
|
+496,128
|
New
|
|
|
10
|
AllianceBernstein
Nashville,
Tennessee
|
$10.9M
|
+$10M
|
+435,209
|
New
|
|
|
11
|
Stifel Financial
St. Louis,
Missouri
|
$10.4M
|
+$9.56M
|
+415,200
|
New
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$8.9M
|
+$8.2M
|
+356,107
|
New
|
|
|
13
|
Emerald Mutual Fund Advisers Trust
Leola,
Pennsylvania
|
$8.81M
|
+$8.12M
|
+352,560
|
New
|
|
|
14
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$7.67M
|
+$7.07M
|
+307,000
|
New
|
|
|
15
|
Yale University
New Haven,
Connecticut
|
$6.25M
|
+$5.76M
|
+250,000
|
New
|
|
|
16
|
Deerfield Management
New York
|
$5.42M
|
+$4.99M
|
+216,761
|
New
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$4.12M
|
+$3.8M
|
+164,904
|
New
|
|
|
18
|
Alyeska Investment Group
Chicago,
Illinois
|
$3.74M
|
+$3.45M
|
+149,651
|
New
|
|
|
19
|
Vanguard Group
Malvern,
Pennsylvania
|
$3.2M
|
+$2.95M
|
+128,102
|
New
|
|
|
20
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$3M
|
+$2.76M
|
+120,000
|
New
|
|
|
21
|
Perceptive Advisors
New York
|
$3M
|
+$2.76M
|
+120,000
|
New
|
|
|
22
|
State Street
Boston,
Massachusetts
|
$2.93M
|
+$2.7M
|
+117,212
|
New
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$2.83M
|
+$2.6M
|
+113,027
|
New
|
|
|
24
|
Bank of America
Charlotte,
North Carolina
|
$2.46M
|
+$2.26M
|
+98,318
|
New
|
|
|
25
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$2.41M
|
+$2.22M
|
+96,218
|
New
|
|