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Black Diamond Therapeutics

104 hedge funds and large institutions have $92M invested in Black Diamond Therapeutics in 2025 Q4 according to their latest regulatory filings, with 27 funds opening new positions, 36 increasing their positions, 25 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

180% more call options, than puts

Call options by funds: $657K | Put options by funds: $235K

125% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 12

44% more repeat investments, than reductions

Existing positions increased: 36 | Existing positions reduced: 25

14% more funds holding

Funds holding: 91104 (+13)

1.67% less ownership

Funds ownership: 68.11%66.45% (-1.7%)

37% less capital invested

Capital invested by funds: $147M → $92M (-$55M)

Holders
104
Holders Change
+13
Holders Change %
+14.29%
% of All Funds
1.26%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
27
Increased
36
Reduced
25
Closed
12
Calls
$657K
Puts
$235K
Net Calls
+$422K
Net Calls Change
-$11K
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$25.8M -$487K -137,508 -1%
NMC
2
NEA Management Company
Maryland
$10.8M
Vanguard Group
3
Vanguard Group
Pennsylvania
$5.32M
Acadian Asset Management
4
Acadian Asset Management
Massachusetts
$3.96M +$4.07M +1,149,050 +239%
Marshall Wace
5
Marshall Wace
United Kingdom
$2.7M -$670K -189,120 -15%
SL
6
Siren LLC
Connecticut
$2.54M
Arrowstreet Capital
7
Arrowstreet Capital
Massachusetts
$2.53M +$509K +143,615 +16%
Jane Street
8
Jane Street
New York
$2.34M +$2.57M +724,503 +305%
Renaissance Technologies
9
Renaissance Technologies
New York
$2.31M +$1.24M +350,335 +58%
BlackRock
10
BlackRock
New York
$2.16M -$495K -139,832 -14%
VPC
11
Vestal Point Capital
New York
$2.11M -$16.6M -4,680,000 -84%
Dimensional Fund Advisors
12
Dimensional Fund Advisors
Texas
$2.08M +$1.42M +401,145 +88%
D.E. Shaw & Co
13
D.E. Shaw & Co
New York
$1.59M +$1.81M +512,129 +357%
Connor, Clark & Lunn Investment Management (CC&L)
14
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.59M +$1.85M +523,064 +397%
AIC
15
AWM Investment Company
New York
$1.52M +$88.5K +25,000 +4%
Fidelity Investments
16
Fidelity Investments
Massachusetts
$1.32M +$310K +87,596 +19%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$1.23M +$18.6K +5,257 +1%
Northern Trust
18
Northern Trust
Illinois
$1.15M -$54.4K -15,362 -3%
Citadel Advisors
19
Citadel Advisors
Florida
$1.03M +$1.51M +425,459 New
WG
20
Winton Group
United Kingdom
$1.02M +$1.49M +421,280 New
Mackenzie Financial
21
Mackenzie Financial
Ontario, Canada
$876K +$1.25M +352,454 New
OSAM
22
O'Shaughnessy Asset Management
Connecticut
$861K +$751K +212,015 +149%
Goldman Sachs
23
Goldman Sachs
New York
$791K -$438K -123,691 -28%
GC
24
Globeflex Capital
California
$742K
Millennium Management
25
Millennium Management
New York
$721K -$1.96M -553,775 -65%

BDTX Hedge Fund Activity: Q4 2025 in Review

104 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Black Diamond Therapeutics (BDTX) for Q4 2025, worth a combined $92M — down 37% from $147M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new BDTX positions and 12 closed out — a net gain of 15 holders — while 36 added to existing stakes and 25 trimmed.

The largest buyer was Acadian Asset Management, adding an estimated $4.07M. The largest seller was Vestal Point Capital, cutting an estimated $16.6M.

  • 104 institutional investors held Black Diamond Therapeutics (BDTX) as of Q4 2025, up from 91 in Q3 2025.
  • Funds reported $92M of Black Diamond Therapeutics stock for Q4 2025, down 37% quarter-over-quarter.
  • 27 funds opened new Black Diamond Therapeutics positions in Q4 2025 and 12 closed out, a net change of +15 holders.
  • The largest Black Diamond Therapeutics buyer in Q4 2025 was Acadian Asset Management, an estimated $4.07M added.
  • The largest Black Diamond Therapeutics seller in Q4 2025 was Vestal Point Capital, an estimated $16.6M sold.

Based on aggregated 13F filings for Q4 2025.