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BioCryst Pharmaceuticals
BCRX

Overview Fund Activity

272 hedge funds and large institutions have $1.31B invested in BioCryst Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 41 funds opening new positions, 110 increasing their positions, 68 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
272
Holders Change
+14
Holders Change %
+5.43%
% of All Funds
3.69%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
41
Increased
110
Reduced
68
Closed
24
Calls
$9.58M
Puts
$4.81M
Net Calls
+$4.78M
Net Calls Change
+$1.17M

Top Buyers

1
Millennium Management
Millennium Management
New York
+$22.7M
2
UBS Group
UBS Group
Switzerland
+$16.2M
3
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$9.55M
4
JAM
Jupiter Asset Management
United Kingdom
+$7.28M
5
PHP
Parkman Healthcare Partners
Connecticut
+$5.88M

Top Sellers

1
ACA
Avoro Capital Advisors
New York
-$23.7M
2
DM
Deerfield Management
New York
-$22.2M
3
RSCM
Rock Springs Capital Management
Maryland
-$18.4M
4
OIM
Oracle Investment Management
Connecticut
-$4.03M
5
WP
Woodline Partners
California
-$3.39M
Name Holding Trade Value Shares
Change 		Shares
Change %
Skandinaviska Enskilda Banken (SEB)
101
Skandinaviska Enskilda Banken (SEB)
Sweden
$855K – – –
EGM
102
Engineers Gate Manager
New York
$848K +$674K +89,804 +386%
MMEA
103
Main Management ETF Advisors
California
$827K +$827K +110,304 New
SEI Investments
104
SEI Investments
Pennsylvania
$821K +$392K +52,277 +91%
Manulife (Manufacturers Life Insurance)
105
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$793K +$16.8K +2,238 +2%
Tudor Investment Corp
106
Tudor Investment Corp
Connecticut
$788K +$41.9K +5,592 +6%
Russell Investments Group
107
Russell Investments Group
United Kingdom
$775K +$565K +75,363 +269%
Los Angeles Capital Management
108
Los Angeles Capital Management
California
$760K +$1.43K +190 +0.2%
CF
109
Corebridge Financial
Texas
$759K -$11.3K -1,500 -1%
PCM
110
Prelude Capital Management
New York
$749K +$749K +99,900 New
SFI
111
Susquehanna Fundamental Investments
Pennsylvania
$722K +$55.8K +7,434 +8%
CV
112
Counterweight Ventures
North Carolina
$700K – – –
Wellington Management Group
113
Wellington Management Group
Massachusetts
$685K +$17.2K +2,291 +3%
HSBC Holdings
114
HSBC Holdings
United Kingdom
$677K +$2.59K +346 +0.4%
Ensign Peak Advisors
115
Ensign Peak Advisors
Utah
$663K – – –
XT
116
XTX Topco
Cayman Islands
$655K +$497K +66,320 +315%
TC
117
TwinBeech Capital
New York
$626K +$626K +83,470 New
Janus Henderson Group
118
Janus Henderson Group
United Kingdom
$624K – – –
Creative Planning
119
Creative Planning
Kansas
$581K -$43.3K -5,776 -7%
DekaBank Deutsche Girozentrale
120
DekaBank Deutsche Girozentrale
Germany
$573K – – –
DA
121
Doliver Advisors
Texas
$557K – – –
GC
122
Grimes & Company
Massachusetts
$545K -$19.3K -2,568 -3%
Verition Fund Management
123
Verition Fund Management
Connecticut
$524K +$116K +15,414 +28%
NFC
124
Northeast Financial Consultants
Connecticut
$492K – – –
Royal Bank of Canada
125
Royal Bank of Canada
Ontario, Canada
$476K +$10.9K +1,458 +2%
3 4
5
6 7