|
1
|
Baker Bros. Advisors
New York
|
$66.6M
|
+$63.8M
|
+3,532,760
|
New
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$65.1M
|
+$62.7M
|
+3,473,239
|
New
|
|
|
3
|
Boxer Capital
San Diego,
California
|
$32.7M
|
+$31.3M
|
+1,733,583
|
New
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$28M
|
+$26.8M
|
+1,486,979
|
New
|
|
|
5
|
Redmile Group
San Francisco,
California
|
$21.5M
|
+$20.6M
|
+1,140,306
|
New
|
|
|
6
|
|
$17.7M
|
+$17M
|
+940,575
|
New
|
|
|
7
|
Samsara BioCapital
Palo Alto,
California
|
$11.1M
|
+$10.7M
|
+591,368
|
New
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$8.38M
|
+$8.03M
|
+444,942
|
New
|
|
|
9
|
Board of Trustees of The Leland Stanford Junior University
Redwood City,
California
|
$8.24M
|
+$7.89M
|
+437,240
|
New
|
|
|
10
|
|
$7.58M
|
+$7.26M
|
+402,463
|
New
|
|
|
11
|
Aisling Capital Management
New York
|
$7.3M
|
+$7M
|
+387,653
|
New
|
|
|
12
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$4.24M
|
+$4.06M
|
+225,000
|
New
|
|
|
13
|
Tekla Capital Management
Boston,
Massachusetts
|
$3.3M
|
+$3.16M
|
+175,000
|
New
|
|
|
14
|
Monashee Investment Management
Boston,
Massachusetts
|
$2.92M
|
+$2.8M
|
+155,000
|
New
|
|
|
15
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.77M
|
+$2.65M
|
+146,975
|
New
|
|
|
16
|
Fidelity Investments
Boston,
Massachusetts
|
$2.22M
|
+$2.12M
|
+117,700
|
New
|
|
|
17
|
Oxford Asset Management
Oxford,
United Kingdom
|
$1.89M
|
+$1.81M
|
+100,121
|
New
|
|
|
18
|
Victory Capital Management
San Antonio,
Texas
|
$1.83M
|
+$1.75M
|
+97,112
|
New
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$1.12M
|
+$1.07M
|
+59,565
|
New
|
|
|
20
|
Alyeska Investment Group
Chicago,
Illinois
|
$925K
|
+$886K
|
+49,095
|
New
|
|
|
21
|
DC Investments Management
Mclean,
Virginia
|
$626K
|
+$600K
|
+33,240
|
New
|
|
|
22
|
Parametric Portfolio Associates
Seattle,
Washington
|
$499K
|
+$478K
|
+26,500
|
New
|
|
|
23
|
Millennium Management
New York
|
$491K
|
+$470K
|
+26,064
|
New
|
|
|
24
|
Pentwater Capital Management
Naples,
Florida
|
$471K
|
+$451K
|
+25,000
|
New
|
|
|
25
|
SG Americas Securities
New York
|
$277K
|
+$265K
|
+14,700
|
New
|
|