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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
Capital World Investors
176
Capital World Investors
California
$11M +$455K +3,145 +4%
B
177
Bailard
California
$11M +$51.5K +356 +0.5%
BCI
178
Brinker Capital Investments
Pennsylvania
$11M +$23.7K +164 +0.2%
OPS
179
Orion Portfolio Solutions
Nebraska
$11M +$23.7K +164 +0.2%
IGAM
180
iA Global Asset Management
Quebec, Canada
$10.9M +$51.7K +357 +0.5%
ZAM
181
Zevin Asset Management
Massachusetts
$10.9M -$339K -2,345 -3%
CUAMC
182
China Universal Asset Management Company
China
$10.9M -$128K -882 -1%
PNC
183
Park National Corp
Ohio
$10.9M -$463K -3,203 -4%
OMC
184
Old Mission Capital
Illinois
$10.6M +$10.1M +70,129 +3,556%
Dodge & Cox
185
Dodge & Cox
California
$10M -$548K -3,785 -5%
New York State Common Retirement Fund
186
New York State Common Retirement Fund
New York
$9.95M +$167K +1,157 +2%
PGFC
187
Peapack-Gladstone Financial Corp
New Jersey
$9.84M +$2.3M +15,914 +31%
National Bank of Canada
188
National Bank of Canada
Quebec, Canada
$9.74M -$3.27M -22,589 -25%
CTA
189
Chesley Taft & Associates
Illinois
$9.7M +$9.3M +64,255 +3,780%
GFM
190
GF Fund Management
China
$9.36M +$345K +2,386 +4%
CP
191
Cumberland Partners
Ontario, Canada
$9.21M +$8.73M +60,366 +2,618%
GT
192
Glenmede Trust
Pennsylvania
$9.16M -$78.9K -545 -0.9%
AI
193
Atria Investments
North Carolina
$9.15M +$1.51M +10,407 +20%
Bessemer Group
194
Bessemer Group
New Jersey
$8.96M +$482K +3,332 +6%
HR
195
Howe & Rusling
New York
$8.9M -$2.56M -17,677 -23%
ACM
196
Altrius Capital Management
North Carolina
$8.65M +$181K +1,250 +2%
VPIM
197
Vanguard Personalized Indexing Management
California
$8.48M +$1.31M +9,070 +19%
Cambridge Investment Research Advisors
198
Cambridge Investment Research Advisors
Iowa
$8.45M +$1.88M +12,983 +29%
BAMCO Inc
199
BAMCO Inc
New York
$8.33M +$412K +2,851 +5%
PFS
200
Prospera Financial Services
Texas
$8.14M +$588K +4,062 +8%

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.