We are live on ! Find out more
AZN icon

AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
Commonwealth Equity Services
151
Commonwealth Equity Services
Massachusetts
$15.3M +$1.11M +7,705 +8%
MSR
152
Main Street Research
Connecticut
$14.9M +$14.6M +101,256 New
FAM
153
Fred Alger Management
New York
$14.6M +$7.2M +49,797 +101%
Federated Hermes
154
Federated Hermes
Pennsylvania
$14.4M -$902K -6,235 -6%
AGP
155
Artia Global Partners
Florida
$14M
Susquehanna International Group
156
Susquehanna International Group
Pennsylvania
$13.8M -$26.6M -183,667 -66%
Corient Private Wealth
157
Corient Private Wealth
Florida
$13.8M -$731K -5,052 -5%
CTI
158
Community Trust & Investment
Kentucky
$13.7M +$228K +1,575 +2%
OFA
159
Oak Family Advisors
Illinois
$13.4M -$1.09M -7,531 -8%
Allspring Global Investments
160
Allspring Global Investments
North Carolina
$12.9M +$1.75M +12,070 +16%
SFM
161
Sphera Funds Management
Israel
$12.9M -$3.62M -25,000 -22%
Osaic Holdings
162
Osaic Holdings
Arizona
$12.5M +$901K +6,228 +8%
Rafferty Asset Management
163
Rafferty Asset Management
New York
$12.5M -$1.97M -13,593 -14%
MCM
164
Marathon Capital Management
Maryland
$12.2M -$128K -886 -1%
FFA
165
First Foundation Advisors
California
$12.2M -$1.73M -11,987 -13%
CFB
166
Cullen/Frost Bankers
Texas
$12.1M -$14K -97 -0.1%
Mercer Global Advisors
167
Mercer Global Advisors
Colorado
$12.1M +$317K +2,192 +3%
GC
168
Guggenheim Capital
Illinois
$12M -$2.62M -18,127 -18%
QCM
169
Quantinno Capital Management
New York
$11.8M +$3.32M +22,974 +40%
ACA
170
Anchor Capital Advisors
Massachusetts
$11.7M -$457K -3,160 -4%
HCM
171
Hilton Capital Management
New York
$11.5M +$114K +788 +1%
TRSOTSOK
172
Teachers Retirement System of the State of Kentucky
Kentucky
$11.4M -$1.09M -7,500 -9%
Nomura Holdings
173
Nomura Holdings
Japan
$11.4M +$6.24M +43,109 +126%
CAPTRUST Financial Advisors
174
CAPTRUST Financial Advisors
North Carolina
$11.2M +$2.36M +16,308 +27%
PHS
175
PFM Health Sciences
California
$11M +$10.9M +75,100 New

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.