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AstraZeneca
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Overview Fund Activity

1,234 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 518 increasing their positions, 372 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,234
Holders Change
+27
Holders Change %
+2.24%
% of All Funds
16.76%
Holding in Top 10
21
Holding in Top 10 Change
+8
Holding in Top 10 Change %
+61.54%
% of All Funds
0.29%
New
151
Increased
518
Reduced
372
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M

Top Buyers

1
Fisher Asset Management
Fisher Asset Management
Washington
+$677M
2
Bank of America
Bank of America
North Carolina
+$574M
3
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
+$182M
4
American Century Companies
American Century Companies
Missouri
+$119M
5
Franklin Resources
Franklin Resources
California
+$119M

Top Sellers

1
Capital International Investors
Capital International Investors
California
-$458M
2
Fayez Sarofim & Co
Fayez Sarofim & Co
Texas
-$452M
3
Jennison Associates
Jennison Associates
New York
-$358M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$240M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$230M
Name Holding Trade Value Shares
Change 		Shares
Change %
MSR
151
Main Street Research
Connecticut
$14.9M +$14.9M +202,512 New
FAM
152
Fred Alger Management
New York
$14.6M +$7.32M +99,595 +101%
Federated Hermes
153
Federated Hermes
Pennsylvania
$14.4M -$916K -12,469 -6%
AGP
154
Artia Global Partners
Florida
$14M – – –
Susquehanna International Group
155
Susquehanna International Group
Pennsylvania
$13.8M -$27M -367,335 -66%
Corient Private Wealth
156
Corient Private Wealth
Florida
$13.8M -$743K -10,103 -5%
CTI
157
Community Trust & Investment
Kentucky
$13.7M +$232K +3,150 +2%
OFA
158
Oak Family Advisors
Illinois
$13.4M -$1.11M -15,061 -8%
Allspring Global Investments
159
Allspring Global Investments
North Carolina
$12.9M +$1.75M +24,141 +16%
SFM
160
Sphera Funds Management
Israel
$12.9M -$3.68M -50,000 -22%
Osaic Holdings
161
Osaic Holdings
Arizona
$12.5M +$916K +12,456 +8%
Rafferty Asset Management
162
Rafferty Asset Management
New York
$12.5M -$2M -27,186 -14%
MCM
163
Marathon Capital Management
Maryland
$12.2M -$130K -1,773 -1%
FFA
164
First Foundation Advisors
California
$12.2M -$1.76M -23,974 -13%
CFB
165
Cullen/Frost Bankers
Texas
$12.1M -$14.2K -193 -0.1%
Mercer Global Advisors
166
Mercer Global Advisors
Colorado
$12.1M +$322K +4,383 +3%
GC
167
Guggenheim Capital
Illinois
$12M -$2.66M -36,254 -18%
QCM
168
Quantinno Capital Management
New York
$11.8M +$3.38M +45,948 +40%
ACA
169
Anchor Capital Advisors
Massachusetts
$11.7M -$465K -6,320 -4%
HCM
170
Hilton Capital Management
New York
$11.5M +$116K +1,576 +1%
TRSOTSOK
171
Teachers Retirement System of the State of Kentucky
Kentucky
$11.4M -$1.1M -15,000 -9%
Nomura Holdings
172
Nomura Holdings
Japan
$11.4M +$6.34M +86,218 +126%
CAPTRUST Financial Advisors
173
CAPTRUST Financial Advisors
North Carolina
$11.2M +$2.4M +32,615 +27%
PHS
174
PFM Health Sciences
California
$11M +$11M +150,200 New
Capital World Investors
175
Capital World Investors
California
$11M +$464K +6,289 +4%
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