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AstraZeneca
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Overview Fund Activity

1,234 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 518 increasing their positions, 372 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,234
Holders Change
+27
Holders Change %
+2.24%
% of All Funds
16.76%
Holding in Top 10
21
Holding in Top 10 Change
+8
Holding in Top 10 Change %
+61.54%
% of All Funds
0.29%
New
151
Increased
518
Reduced
372
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M

Top Buyers

1
Fisher Asset Management
Fisher Asset Management
Washington
+$677M
2
Bank of America
Bank of America
North Carolina
+$574M
3
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
+$182M
4
American Century Companies
American Century Companies
Missouri
+$119M
5
Franklin Resources
Franklin Resources
California
+$119M

Top Sellers

1
Capital International Investors
Capital International Investors
California
-$458M
2
Fayez Sarofim & Co
Fayez Sarofim & Co
Texas
-$452M
3
Jennison Associates
Jennison Associates
New York
-$358M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$240M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$230M
Name Holding Trade Value Shares
Change 		Shares
Change %
AA
126
ABC Arbitrage
France
$20.2M +$20.2M +274,642 New
ATI
127
Act Two Investors
California
$20M +$10.2M +138,941 +104%
MML Investors Services
128
MML Investors Services
Massachusetts
$19.6M +$751K +10,223 +4%
Baird Financial Group
129
Baird Financial Group
Wisconsin
$19.5M +$69.5K +945 +0.4%
AssetMark Inc
130
AssetMark Inc
California
$19.4M +$1.91M +26,014 +11%
Jane Street
131
Jane Street
New York
$19.1M +$8.44M +114,787 +79%
OSAM
132
O'Shaughnessy Asset Management
Connecticut
$18.8M +$5.67M +77,152 +43%
M&T Bank
133
M&T Bank
New York
$18.7M +$858K +11,672 +5%
Cetera Investment Advisers
134
Cetera Investment Advisers
Illinois
$18.5M +$4.15M +56,449 +29%
Charles Schwab
135
Charles Schwab
California
$18.4M -$110M -1,493,854 -86%
TCM
136
Tang Capital Management
California
$18.4M +$7.35M +100,000 +67%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
137
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$18.2M +$6.24M +84,844 +52%
PNC Financial Services Group
138
PNC Financial Services Group
Pennsylvania
$18.2M +$2.1M +28,554 +13%
CIBC Asset Management
139
CIBC Asset Management
Ontario, Canada
$17.6M +$370K +5,030 +2%
SIA
140
Sit Investment Associates
Minnesota
$17.5M +$5.26M +71,563 +43%
US Bancorp
141
US Bancorp
Minnesota
$17.4M -$182K -2,472 -1%
QCM
142
QRG Capital Management
Illinois
$17.3M +$1.07M +14,624 +7%
CSS
143
Cubist Systematic Strategies
Connecticut
$17.3M +$13.1M +178,792 +320%
DIA
144
Davidson Investment Advisors
Montana
$17.2M +$475K +6,456 +3%
HF
145
HRT Financial
New York
$17.1M +$17.1M +232,892 New
FDCDDQ
146
Federation des caisses Desjardins du Quebec
Quebec, Canada
$16.9M +$1.14M +15,554 +7%
WA
147
Waverly Advisors
Alabama
$16.5M +$14.7M +199,935 +828%
Qube Research & Technologies (QRT)
148
Qube Research & Technologies (QRT)
United Kingdom
$16.4M -$27M -366,911 -62%
William Blair & Company
149
William Blair & Company
Illinois
$16M -$747K -10,161 -4%
Commonwealth Equity Services
150
Commonwealth Equity Services
Massachusetts
$15.3M +$1.13M +15,410 +8%
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6
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