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AstraZeneca

1,404 hedge funds and large institutions have $45.2B invested in AstraZeneca in 2025 Q4 according to their latest regulatory filings, with 264 funds opening new positions, 500 increasing their positions, 410 reducing their positions, and 119 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,404
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
22
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$597M
Puts
$420M
Net Calls
Net Calls Change

Top Buyers

1 +$420M
2 +$412M
3 +$327M
4
Citigroup
Citigroup
New York
+$204M
5
Barclays
Barclays
United Kingdom
+$180M

Top Sellers

1 -$924M
2 -$831M
3 -$550M
4
Primecap Management
Primecap Management
California
-$258M
5
Citadel Advisors
Citadel Advisors
Florida
-$241M
Name Holding Trade Value Shares
Change
Change in
Stake
AP
1426
Americana Partners
Texas
LIM
1427
Longfellow Investment Management
Massachusetts
GP
1428
Guardian Partners
Canada
IMC Chicago
1429
IMC Chicago
Illinois
Tudor Investment Corp
1430
Tudor Investment Corp
Connecticut
CCIA
1431
Campbell & Co Investment Adviser
Maryland
MPCL
1432
My Personal CFO LLC
Washington
AIC
1433
Aurora Investment Counsel
Georgia
HI
1434
Horizon Investments
North Carolina
OC
1435
Oppenheimer & Co
New York
EF
1436
Empowered Funds
Pennsylvania
LFAS
1437
Level Four Advisory Services
Texas
EGM
1438
Engineers Gate Manager
New York
LIP
1439
Lighthouse Investment Partners
Florida
Optiver Holding
1440
Optiver Holding
Netherlands
GIC
1441
Generali Investments CEE
Czech Republic
NSEDCP
1442
NJ State Employees Deferred Compensation Plan
New Jersey
P
1443
Pitcairn
Pennsylvania
BHCM
1444
Brevan Howard Capital Management
Jersey
CLGM
1445
Capitolis Liquid Global Markets
New York
LFA
1446
Legacy Financial Advisors
Kentucky
BCA
1447
Bay Colony Advisors
Massachusetts
SMH
1448
Sanders Morris Harris
Texas
MIP
1449
Marietta Investment Partners
Wisconsin
SN
1450
Sittner & Nelson
Oregon