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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
CWM
1276
CIBC World Markets
New York
-$845K -6,451 Closed
BRA
1277
Bender Robert & Associates
California
-$799K -6,101 Closed
SFI
1278
Siemens Fonds Invest
Germany
-$713K -5,437 Closed
GCM
1279
Graham Capital Management
Connecticut
-$664K -5,070 Closed
FTUS
1280
Flow Traders U.S.
New York
-$543K -4,146 Closed
JGGDR
1281
JGP Global Gestao de Recursos
Brazil
-$378K -2,881 Closed
ES
1282
Eagle Strategies
New York
-$376K -2,868 Closed
Simplex Trading
1283
Simplex Trading
Illinois
-$398K -2,754 Closed
IAIM
1284
International Assets Investment Management
Florida
-$336K -2,553 Closed
WPW
1285
Waldron Private Wealth
Pennsylvania
-$307K -2,345 Closed
SFG
1286
SevenBridge Financial Group
Pennsylvania
-$319K -2,192 Closed
BAM
1287
Blueshift Asset Management
New Jersey
-$285K -2,178 Closed
G
1288
GenTrust
Florida
-$284K -2,171 Closed
WH
1289
Willner & Heller
California
-$276K -2,104 Closed
AIA
1290
Angeles Investment Advisors
California
-$272K -2,074 Closed
FTWA
1291
Fifth Third Wealth Advisors
Ohio
-$270K -2,060 Closed
AT
1292
American Trust
Kentucky
-$266K -2,030 Closed
CGA
1293
Compound Global Advisors
Washington
-$262K -2,000 Closed
GCP
1294
GSA Capital Partners
United Kingdom
-$259K -1,976 Closed
CPIA
1295
Cornell Pochily Investment Advisors
New York
-$253K -1,928 Closed
SIM
1296
Stratos Investment Management
Ohio
-$250K -1,911 Closed
LGF
1297
LGT Group Foundation
Liechtenstein
-$233K -1,777 Closed
TAM
1298
Tucker Asset Management
Colorado
-$222K -1,694 Closed
FA
1299
FC Advisory
Pennsylvania
-$220K -1,680 Closed
BC
1300
Bridgefront Capital
Texas
-$213K -1,625 Closed

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.