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AstraZeneca
AZN

1,287 hedge funds and large institutions have $37.9B invested in AstraZeneca in 2025 Q3 according to their latest regulatory filings, with 159 funds opening new positions, 546 increasing their positions, 359 reducing their positions, and 76 closing their positions.

New
Increased
Maintained
Reduced
Closed

109% more first-time investments, than exits

New positions opened: 159 | Existing positions closed: 76

91% more funds holding in top 10

Funds holding in top 10: 11 → 21 (+10)

84% more call options, than puts

Call options by funds: $559M | Put options by funds: $303M

52% more repeat investments, than reductions

Existing positions increased: 546 | Existing positions reduced: 359

9% more capital invested

Capital invested by funds: $34.7B → $37.9B (+$3.21B)

5% more funds holding

Funds holding: 1,222 → 1,287 (+65)

0.04% less ownership

Funds ownership: 8% → 7.96% (-0.04%)

Holders
1,287
Holders Change
+65
Holders Change %
+5.32%
% of All Funds
16.89%
Holding in Top 10
21
Holding in Top 10 Change
+10
Holding in Top 10 Change %
+90.91%
% of All Funds
0.28%
New
159
Increased
546
Reduced
359
Closed
76
Calls
$559M
Puts
$303M
Net Calls
+$256M
Net Calls Change
-$80.8M

Top Buyers

Rank Fund Capital Flow
1
Citigroup
Citigroup
New York
+$219M
2
Bank of Montreal
Bank of Montreal
Ontario, Canada
+$204M
3
Holocene Advisors
Holocene Advisors
New York
+$137M
4
Citadel Advisors
Citadel Advisors
Florida
+$133M
5
Goldman Sachs
Goldman Sachs
New York
+$126M

Top Sellers

Rank Fund Capital Flow
1
Jennison Associates
Jennison Associates
New York
-$642M
2
Capital International Investors
Capital International Investors
California
-$481M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$213M
4
Wellington Management Group
Wellington Management Group
Massachusetts
-$154M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$127M
Name Holding Trade Value Shares
Change 		Change in
Stake
AW
1251
Avion Wealth
Texas
$5K – – –
T
1252
Tidemark
California
$4.91K – – –
PFSC
1253
Peoples Financial Services Corp
Pennsylvania
$4.76K – – –
RWM
1254
RMG Wealth Management
Wisconsin
$4.7K – – –
ME
1255
McIlrath & Eck
Washington
$4.68K – – –
SJIM
1256
St. Johns Investment Management
Florida
$4.45K – – –
TTIC
1257
Tower Trust & Investment Company
Iowa
$4.22K – – –
NIG
1258
NFJ Investment Group
Texas
$3.99K – – –
MSWA
1259
Marshall & Sterling Wealth Advisors
New York
$3.45K +$757 +5 +28%
WAS
1260
Winch Advisory Services
Wisconsin
$3.37K – – –
MEG
1261
Millstone Evans Group
Colorado
$3.22K – – –
HC
1262
Hara Capital
Washington
$3.07K – – –
PWAM
1263
Private Wealth Asset Management
Iowa
$3.07K – – –
CI
1264
CX Institutional
Indiana
$3K – – –
BL
1265
BFSG LLC
California
$2.76K – – –
EWP
1266
Elevation Wealth Partners
California
$2.15K – – –
GGI
1267
Godsey & Gibb Inc
Virginia
$2.07K -$1.67K -11 -44%
KG
1268
Kilter Group
New York
$2K +$605 +4 +44%
GA
1269
Guerra Advisors
Florida
$1.73K +$1.67K +11 New
HHGA
1270
Halbert Hargrove Global Advisors
California
$1.61K +$1.67K +11 New
AFWM
1271
Abich Financial Wealth Management
Virginia
$1.61K +$1.67K +11 New
GIM
1272
Gold Investment Management
Alberta, Canada
$1.53K – – –
SC
1273
Solstein Capital
California
$1.46K – – –
CTA
1274
Colonial Trust Advisors
South Carolina
$1.38K – – –
FFO
1275
Fortitude Family Office
Arizona
$1.03K – – –
49 50
51
52 53

AZN Hedge Fund Activity: Q3 2025 in Review

1,287 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q3 2025, worth a combined $37.9B — up 9.2% from $34.7B a quarter earlier.

Buyers outnumbered sellers: 159 funds opened new AZN positions and 76 closed out — a net gain of 83 holders — while 546 added to existing stakes and 359 trimmed.

The largest buyer was Citigroup, adding an estimated $219M. The largest seller was Jennison Associates, cutting an estimated $642M.

  • 1,287 institutional investors held AstraZeneca (AZN) as of Q3 2025, up from 1,222 in Q2 2025.
  • Funds reported $37.9B of AstraZeneca stock for Q3 2025, up 9.2% quarter-over-quarter.
  • 159 funds opened new AstraZeneca positions in Q3 2025 and 76 closed out, a net change of +83 holders.
  • The largest AstraZeneca buyer in Q3 2025 was Citigroup, an estimated $219M added.
  • The largest AstraZeneca seller in Q3 2025 was Jennison Associates, an estimated $642M sold.

Based on aggregated 13F filings for Q3 2025.