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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
SI
1251
Sofinnova Investments
California
-$42.7M -325,672 Closed
Pictet Asset Management
1252
Pictet Asset Management
Switzerland
-$37.3M -284,650 Closed
VPC
1253
Vestal Point Capital
New York
-$31.1M -237,500 Closed
SCM
1254
Soleus Capital Management
Connecticut
-$26.8M -204,500 Closed
IHAM
1255
Integral Health Asset Management
New York
-$14.7M -112,500 Closed
Voloridge Investment Management
1256
Voloridge Investment Management
Florida
-$12.9M -98,331 Closed
KHLMVGHM
1257
Kranot Hishtalmut Le Morim Ve Gananot Havera Menahelet
Israel
-$9.99M -76,310 Closed
GIM
1258
Generate Investment Management
New Zealand
-$7.92M -60,426 Closed
MIF
1259
Mediolanum International Funds
Ireland
-$7.39M -56,502 Closed
QIM
1260
Quantitative Investment Management
Virginia
-$7.18M -54,794 Closed
EP
1261
Eversept Partners
New York
-$6.73M -51,331 Closed
Two Sigma Advisers
1262
Two Sigma Advisers
New York
-$5.64M -43,050 Closed
SFAM
1263
Springhill Fund Asset Management
Hong Kong
-$5.01M -38,250 Closed
KHLMTHM
1264
Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet
Israel
-$3.43M -26,190 Closed
CM
1265
Crestline Management
Texas
-$2.45M -18,668 Closed
Group One Trading
1266
Group One Trading
Illinois
-$2.37M -16,379 Closed
BCM
1267
Bayesian Capital Management
New York
-$2.1M -16,050 Closed
DP
1268
Diadema Partners
New Jersey
-$3.93M -15,000 Closed
CFGS
1269
Concourse Financial Group Securities
Alabama
-$1.91M -13,976 Closed
EAM
1270
Empirical Asset Management
Massachusetts
-$44.6K -11,924 Closed
FHB
1271
First Hawaiian Bank
Hawaii
-$1.48M -11,265 Closed
PCMU
1272
Paragon Capital Management (Utah)
Utah
-$1.26M -9,602 Closed
PFM
1273
Potomac Fund Management
Florida
-$1.1M -8,382 Closed
AC
1274
AXQ Capital
New Jersey
-$1.03M -7,884 Closed
PCMH
1275
Polymer Capital Management (HK)
Hong Kong
-$1.01M -7,675 Closed

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.