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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
CAG
101
Crestwood Advisors Group
Massachusetts
$31.8M +$30.9M +213,303 +7,350%
FG
102
Foresight Group
United Kingdom
$31.6M +$15.8M +108,912 New
BGIM
103
Brandywine Global Investment Management
Pennsylvania
$31.2M -$301K -2,080 -1%
Twin Tree Management
104
Twin Tree Management
Texas
$30.4M +$23.7M +164,041 +385%
Mackenzie Financial
105
Mackenzie Financial
Ontario, Canada
$29.6M -$9.2M -63,594 -24%
CCMG
106
Clark Capital Management Group
Pennsylvania
$28.8M +$27.6M +190,561 +3,793%
BCM
107
Becker Capital Management
Oregon
$28M +$153K +1,060 +0.6%
ITP
108
Iron Triangle Partners
Connecticut
$27.7M +$27.2M +188,165 New
Pathstone Holdings
109
Pathstone Holdings
New Jersey
$27.3M +$109K +751 +0.4%
CCM
110
Chilton Capital Management
Texas
$27.3M +$607K +4,193 +2%
Macquarie Group
111
Macquarie Group
Australia
$27.1M -$10.5M -72,619 -28%
SO
112
STRS Ohio
Ohio
$26.8M
Walleye Capital
113
Walleye Capital
New York
$25.8M -$936K -6,468 -4%
SAM
114
Silvercrest Asset Management
New York
$23.7M +$2.47M +17,068 +12%
CGPCS
115
Capital Group Private Client Services
California
$23.5M -$9.66M -66,783 -29%
Wealth Enhancement Advisory Services
116
Wealth Enhancement Advisory Services
Minnesota
$22.9M +$402K +2,778 +2%
MIM
117
Martin Investment Management
Florida
$22.9M +$182K +1,255 +0.8%
FLPIM
118
F.L. Putnam Investment Management
Massachusetts
$22.5M +$941K +6,501 +4%
PAS
119
Professional Advisory Services
Florida
$22.4M -$1.99M -13,756 -8%
SC
120
Scotia Capital
Ontario, Canada
$22.3M +$5.19M +35,844 +31%
Renaissance Technologies
121
Renaissance Technologies
New York
$22M +$20.2M +139,415 +1,369%
Janney Montgomery Scott
122
Janney Montgomery Scott
Pennsylvania
$21.9M +$21.6M +149,155 New
CII
123
Capital International Inc
California
$21.8M +$263K +1,819 +1%
KCM
124
Kornitzer Capital Management
Kansas
$21.7M -$310K -2,146 -1%
Creative Planning
125
Creative Planning
Kansas
$21.4M +$3.39M +23,464 +19%

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.