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AstraZeneca
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Overview Fund Activity

1,203 hedge funds and large institutions have $34.6B invested in AstraZeneca in 2025 Q2 according to their latest regulatory filings, with 99 funds opening new positions, 457 increasing their positions, 430 reducing their positions, and 108 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,203
Holders Change
-31
Holders Change %
-2.51%
% of All Funds
16.12%
Holding in Top 10
11
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-47.62%
% of All Funds
0.15%
New
99
Increased
457
Reduced
430
Closed
108
Calls
$596M
Puts
$259M
Net Calls
+$337M
Net Calls Change
-$224M

Top Buyers

1
Fayez Sarofim & Co
Fayez Sarofim & Co
Texas
+$166M
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$137M
3
Jennison Associates
Jennison Associates
New York
+$112M
4
Raymond James Financial
Raymond James Financial
Florida
+$104M
5
OTPPB
Ontario Teachers' Pension Plan Board
Ontario, Canada
+$96.9M

Top Sellers

1
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$359M
2
Morgan Stanley
Morgan Stanley
New York
-$248M
3
SFM
Soros Fund Management
New York
-$202M
4
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
-$170M
5
Fidelity Investments
Fidelity Investments
Massachusetts
-$122M
Name Holding Trade Value Shares
Change 		Shares
Change %
WOC
1201
West Oak Capital
California
$122 – – –
PPA
1202
Painted Porch Advisors
California
$77 +$77 +1 New
SFM
1203
Soros Fund Management
New York
– -$202M -2,742,498 Closed
Optiver Holding
1204
Optiver Holding
Netherlands
– -$40.6M -552,012 Closed
Twin Tree Management
1205
Twin Tree Management
Texas
– -$30.4M -413,292 Closed
ITP
1206
Iron Triangle Partners
Connecticut
– -$27.7M -376,330 Closed
SO
1207
STRS Ohio
Ohio
– -$26.8M -365,000 Closed
MSR
1208
Main Street Research
Connecticut
– -$14.9M -202,512 Closed
Nomura Holdings
1209
Nomura Holdings
Japan
– -$11.4M -154,439 Closed
PHS
1210
PFM Health Sciences
California
– -$11M -150,200 Closed
OMC
1211
Old Mission Capital
Illinois
– -$10.6M -144,202 Closed
TC
1212
Trium Capital
United Kingdom
– -$7.54M -102,641 Closed
PE
1213
Point72 Europe
United Kingdom
– -$6.55M -89,112 Closed
Wolverine Trading
1214
Wolverine Trading
Illinois
– -$5.47M -74,174 Closed
SGH
1215
Sivik Global Healthcare
Connecticut
– -$5.15M -70,000 Closed
WC
1216
Wexford Capital
Florida
– -$303K -46,352 Closed
JG
1217
Jain Global
New York
– -$3.15M -42,834 Closed
AIP
1218
Arrowpoint Investment Partners
Singapore
– -$2.98M -40,500 Closed
TI
1219
Trexquant Investment
Connecticut
– -$2.96M -40,263 Closed
Massachusetts Financial Services
1220
Massachusetts Financial Services
Massachusetts
– -$2.83M -38,496 Closed
CF
1221
Corebridge Financial
Texas
– -$2.7M -36,681 Closed
EAM
1222
Exome Asset Management
New York
– -$4.73M -32,534 Closed
XT
1223
XTX Topco
Cayman Islands
– -$1.63M -22,221 Closed
FMI
1224
F/M Investments
District of Columbia
– -$1.55M -21,147 Closed
WH
1225
Wallace Hart
Kentucky
– -$1.32M -18,004 Closed
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