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AstraZeneca
AZN

1,287 hedge funds and large institutions have $37.9B invested in AstraZeneca in 2025 Q3 according to their latest regulatory filings, with 159 funds opening new positions, 546 increasing their positions, 359 reducing their positions, and 76 closing their positions.

New
Increased
Maintained
Reduced
Closed

109% more first-time investments, than exits

New positions opened: 159 | Existing positions closed: 76

91% more funds holding in top 10

Funds holding in top 10: 11 → 21 (+10)

84% more call options, than puts

Call options by funds: $559M | Put options by funds: $303M

52% more repeat investments, than reductions

Existing positions increased: 546 | Existing positions reduced: 359

9% more capital invested

Capital invested by funds: $34.7B → $37.9B (+$3.21B)

5% more funds holding

Funds holding: 1,222 → 1,287 (+65)

0.04% less ownership

Funds ownership: 8% → 7.96% (-0.04%)

Holders
1,287
Holders Change
+65
Holders Change %
+5.32%
% of All Funds
16.89%
Holding in Top 10
21
Holding in Top 10 Change
+10
Holding in Top 10 Change %
+90.91%
% of All Funds
0.28%
New
159
Increased
546
Reduced
359
Closed
76
Calls
$559M
Puts
$303M
Net Calls
+$256M
Net Calls Change
-$80.8M

Top Buyers

Rank Fund Capital Flow
1
Citigroup
Citigroup
New York
+$219M
2
Bank of Montreal
Bank of Montreal
Ontario, Canada
+$204M
3
Holocene Advisors
Holocene Advisors
New York
+$137M
4
Citadel Advisors
Citadel Advisors
Florida
+$133M
5
Goldman Sachs
Goldman Sachs
New York
+$126M

Top Sellers

Rank Fund Capital Flow
1
Jennison Associates
Jennison Associates
New York
-$642M
2
Capital International Investors
Capital International Investors
California
-$481M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$213M
4
Wellington Management Group
Wellington Management Group
Massachusetts
-$154M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$127M
Name Holding Trade Value Shares
Change 		Change in
Stake
KA
1001
Kovack Advisors
Florida
$209K -$13.3K -88 -6%
NQWM
1002
Northwest Quadrant Wealth Management
Oregon
$209K +$206K +1,363 New
CIA
1003
Capital Investment Advisors
Georgia
$209K +$206K +1,363 New
FCH
1004
Freestone Capital Holdings
Washington
$208K +$205K +1,357 New
VF
1005
Virtu Financial
New York
$208K +$206K +1,359 New
Allianz Asset Management
1006
Allianz Asset Management
Germany
$208K +$205K +1,353 New
EFSCE
1007
Enterprise Financial Services Corp (EFSC)
Missouri
$206K +$203K +1,344 New
FG
1008
Foster Group
Iowa
$204K +$201K +1,327 New
SCM
1009
Saxony Capital Management
Missouri
$203K +$200K +1,324 New
SG
1010
StoneX Group
New York
$203K +$200K +1,322 New
PAS
1011
Point72 Asia (Singapore)
Singapore
$202K +$199K +1,318 New
NL
1012
Navalign LLC
California
$201K +$199K +1,313 New
1SB
1013
1ST Source Bank
Indiana
$201K +$198K +1,311 New
CPA
1014
Capital Performance Advisors
California
$201K +$198K +1,309 New
KA
1015
Klingman & Associates
New York
$200K +$198K +1,307 New
1CP
1016
17 Capital Partners
Arizona
$200K +$198K +1,305 New
TF
1017
Tompkins Financial
New York
$192K – – –
IRC
1018
Investors Research Corp
Georgia
$190K +$16.6K +110 +10%
AAS
1019
Ameritas Advisory Services
Nebraska
$186K -$383K -2,532 -68%
KOCAA
1020
Knights of Columbus Asset Advisors
Connecticut
$175K +$4.09K +27 +2%
CIAM
1021
Caitong International Asset Management
Hong Kong
$173K +$7.87K +52 +5%
SGK
1022
Steigerwald Gordon & Koch
Virginia
$172K +$170K +1,124 New
WA
1023
Westfuller Advisors
New York
$163K +$161K +1,063 New
FWA
1024
Flagship Wealth Advisors
Massachusetts
$160K +$1.67K +11 +1%
WA
1025
WPG Advisers
Maryland
$157K +$3.33K +22 +2%
39 40
41
42 43

AZN Hedge Fund Activity: Q3 2025 in Review

1,287 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q3 2025, worth a combined $37.9B — up 9.2% from $34.7B a quarter earlier.

Buyers outnumbered sellers: 159 funds opened new AZN positions and 76 closed out — a net gain of 83 holders — while 546 added to existing stakes and 359 trimmed.

The largest buyer was Citigroup, adding an estimated $219M. The largest seller was Jennison Associates, cutting an estimated $642M.

  • 1,287 institutional investors held AstraZeneca (AZN) as of Q3 2025, up from 1,222 in Q2 2025.
  • Funds reported $37.9B of AstraZeneca stock for Q3 2025, up 9.2% quarter-over-quarter.
  • 159 funds opened new AstraZeneca positions in Q3 2025 and 76 closed out, a net change of +83 holders.
  • The largest AstraZeneca buyer in Q3 2025 was Citigroup, an estimated $219M added.
  • The largest AstraZeneca seller in Q3 2025 was Jennison Associates, an estimated $642M sold.

Based on aggregated 13F filings for Q3 2025.