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AstraZeneca

1,495 hedge funds and large institutions have $196B invested in AstraZeneca in 2026 Q2 according to their latest regulatory filings, with 262 funds opening new positions, 521 increasing their positions, 489 reducing their positions, and 120 closing their positions.

New
Increased
Maintained
Reduced
Closed

118% more first-time investments, than exits

New positions opened: 262 | Existing positions closed: 120

29% more capital invested

Capital invested by funds: $152B → $196B (+$44.1B)

8% more funds holding

Funds holding: 1,3831,495 (+112)

7% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 489

15% less funds holding in top 10

Funds holding in top 10: 7261 (-11)

24.42% less ownership

Funds ownership: 24.42%0% (-24%)

42% less call options, than puts

Call options by funds: $704M | Put options by funds: $1.21B

Holders
1,495
Holders Change
+112
Holders Change %
+8.1%
% of All Funds
18.07%
Holding in Top 10
61
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-15.28%
% of All Funds
0.74%
New
262
Increased
521
Reduced
489
Closed
120
Calls
$704M
Puts
$1.21B
Net Calls
-$507M
Net Calls Change
+$89.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Zurich Cantonal Bank
76
Zurich Cantonal Bank
Switzerland
$352M -$21.4M -114,035 -6%
Jones Financial Companies
77
Jones Financial Companies
Missouri
$315M +$125M +666,460 +66%
TD Asset Management
78
TD Asset Management
Ontario, Canada
$304M -$64.8M -344,426 -18%
Wells Fargo
79
Wells Fargo
California
$303M +$9.74M +51,795 +3%
AAB
80
ABN AMRO Bank
Netherlands
$297M -$160M -852,775 -35%
LIP
81
Liontrust Investment Partners
United Kingdom
$297M +$298M +1,586,940 New
Canada Life
82
Canada Life
Manitoba, Canada
$285M +$846K +4,497 +0.3%
Ninety One (UK)
83
Ninety One (UK)
United Kingdom
$284M -$99.5M -529,006 -26%
William Blair Investment Management
84
William Blair Investment Management
Illinois
$283M -$80.4M -427,360 -22%
Caisse de Depot et Placement du Quebec (CDPQ)
85
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$274M +$275M +1,463,843 New
ISS
86
Intesa Sanpaolo SpA.
Italy
$274M +$57.5M +305,904 +26%
Assenagon Asset Management
87
Assenagon Asset Management
Luxembourg
$256M +$79.5M +422,866 +46%
Canada Pension Plan Investment Board
88
Canada Pension Plan Investment Board
Ontario, Canada
$253M +$129M +685,768 +104%
American Century Companies
89
American Century Companies
Missouri
$250M -$91.5M -486,668 -27%
WCM Investment Management
90
WCM Investment Management
California
$249M +$247M +1,310,660 New
AIM
91
Artemis Investment Management
United Kingdom
$239M -$31.1M -165,296 -11%
PCH
92
Polar Capital Holdings
United Kingdom
$237M +$235M +1,247,549 New
VOYA Investment Management
93
VOYA Investment Management
Georgia
$233M -$120M -636,269 -34%
Korea Investment Corp
94
Korea Investment Corp
South Korea
$232M -$19.4M -103,120 -8%
1832 Asset Management
95
1832 Asset Management
Ontario, Canada
$231M +$108M +574,321 +90%
MSE
96
MUFG Securities EMEA
United Kingdom
$222M +$60.7M +322,501 +37%
D.E. Shaw & Co
97
D.E. Shaw & Co
New York
$208M +$201M +1,069,588 +4,277%
Ohio Public Employees Retirement System (OPERS)
98
Ohio Public Employees Retirement System (OPERS)
Ohio
$201M +$21.4M +113,570 +12%
CIS
99
Capital International Sarl
California
$187M +$15.4M +81,814 +9%
Citadel Advisors
100
Citadel Advisors
Florida
$184M -$169M -899,750 -48%

AZN Hedge Fund Activity: Q2 2026 in Review

1,495 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q2 2026, worth a combined $196B — up 29% from $152B a quarter earlier.

Buyers outnumbered sellers: 262 funds opened new AZN positions and 120 closed out — a net gain of 142 holders — while 521 added to existing stakes and 489 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $900M. The largest seller was T. Rowe Price Associates, cutting an estimated $540M.

  • 1,495 institutional investors held AstraZeneca (AZN) as of Q2 2026, up from 1,383 in Q1 2026.
  • Funds reported $196B of AstraZeneca stock for Q2 2026, up 29% quarter-over-quarter.
  • 262 funds opened new AstraZeneca positions in Q2 2026 and 120 closed out, a net change of +142 holders.
  • The largest AstraZeneca buyer in Q2 2026 was Wellington Management Group, an estimated $900M added.
  • The largest AstraZeneca seller in Q2 2026 was T. Rowe Price Associates, an estimated $540M sold.

Based on aggregated 13F filings for Q2 2026.