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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
GD
726
Grandfield & Dodd
New York
$478K -$145 -1 -0%
GSEP
727
Golden State Equity Partners
California
$474K +$46.7K +323 +11%
AW
728
Alteri Wealth
California
$474K +$183K +1,265 +65%
AFW
729
Avantra Family Wealth
Pennsylvania
$468K -$197K -1,365 -30%
HIIFS
730
Harel Insurance Investments & Financial Services
Israel
$467K +$59.5K +411 +15%
CSP
731
Cary Street Partners
Virginia
$463K -$29.8K -206 -6%
JFG
732
Jefferies Financial Group
New York
$463K +$455K +3,148 New
AHL
733
Abel Hall LLC
Louisiana
$459K +$130K +900 +40%
CCA
734
Cobblestone Capital Advisors
New York
$454K +$191K +1,322 +75%
XF
735
XML Financial
Maryland
$452K -$18.1K -125 -4%
CH
736
Cromwell Holdings
Wyoming
$450K
DT
737
Diversified Trust
Tennessee
$446K +$31.8K +220 +8%
WJWM
738
Williams Jones Wealth Management
New York
$442K +$6.08K +42 +1%
FFA
739
Farther Finance Advisors
California
$442K +$51.1K +353 +13%
IA
740
Integrity Alliance
Iowa
$440K +$433K +2,991 New
GCM
741
Gallacher Capital Management
Colorado
$438K +$24K +166 +6%
EWA
742
EverSource Wealth Advisors
Alabama
$436K -$289 -2 -0.1%
HTC
743
Haverford Trust Company
Pennsylvania
$435K +$2.31K +16 +0.5%
VF
744
Virtu Financial
New York
$434K -$305K -2,108 -42%
CYG
745
Clean Yield Group
Vermont
$434K
BBHC
746
Brown Brothers Harriman & Co
New York
$433K -$61.3K -424 -13%
MNBTD
747
Moody National Bank Trust Division
Texas
$433K +$96.4K +666 +29%
AGC
748
Aspen Grove Capital
Colorado
$430K +$181K +1,248 +74%
BCG
749
Breakwater Capital Group
New Jersey
$429K +$422K +2,919 New
MSAM
750
Moloney Securities Asset Management
Missouri
$427K +$868 +6 +0.2%

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.