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AstraZeneca
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Overview Fund Activity

1,203 hedge funds and large institutions have $34.6B invested in AstraZeneca in 2025 Q2 according to their latest regulatory filings, with 99 funds opening new positions, 457 increasing their positions, 430 reducing their positions, and 108 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,203
Holders Change
-31
Holders Change %
-2.51%
% of All Funds
16.12%
Holding in Top 10
11
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-47.62%
% of All Funds
0.15%
New
99
Increased
457
Reduced
430
Closed
108
Calls
$596M
Puts
$259M
Net Calls
+$337M
Net Calls Change
-$224M

Top Buyers

1
Fayez Sarofim & Co
Fayez Sarofim & Co
Texas
+$166M
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$137M
3
Jennison Associates
Jennison Associates
New York
+$112M
4
Raymond James Financial
Raymond James Financial
Florida
+$104M
5
OTPPB
Ontario Teachers' Pension Plan Board
Ontario, Canada
+$96.9M

Top Sellers

1
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$359M
2
Morgan Stanley
Morgan Stanley
New York
-$248M
3
SFM
Soros Fund Management
New York
-$202M
4
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
-$170M
5
Fidelity Investments
Fidelity Investments
Massachusetts
-$122M
Name Holding Trade Value Shares
Change 		Shares
Change %
Stifel Financial
51
Stifel Financial
Missouri
$80.2M -$3.54M -50,686 -4%
Millennium Management
52
Millennium Management
New York
$80M +$13.5M +193,219 +20%
NC
53
Nicholas Company
Wisconsin
$79.6M -$1.5M -21,410 -2%
VOYA Investment Management
54
VOYA Investment Management
Georgia
$78.9M -$75.3M -1,078,020 -49%
Lazard Asset Management
55
Lazard Asset Management
New York
$78.7M -$125K -1,784 -0.2%
First Trust Advisors
56
First Trust Advisors
Illinois
$77.5M +$15.2M +217,595 +24%
EAM
57
Erste Asset Management
Austria
$70.7M +$3.59M +51,313 +5%
LPL Financial
58
LPL Financial
California
$69.9M +$8.2M +117,349 +13%
CCM
59
Causeway Capital Management
California
$66.6M +$6.68M +95,561 +11%
State Street
60
State Street
Massachusetts
$65.6M -$4.16M -59,558 -6%
HighTower Advisors
61
HighTower Advisors
Illinois
$64.7M +$12.6M +180,680 +24%
Bank of New York Mellon
62
Bank of New York Mellon
New York
$64.7M -$4.79M -68,487 -7%
Citigroup
63
Citigroup
New York
$64.6M +$9.44M +135,107 +17%
TD Asset Management
64
TD Asset Management
Ontario, Canada
$63.5M -$14M -199,851 -18%
Two Sigma Investments
65
Two Sigma Investments
New York
$60M +$28.2M +403,965 +89%
Russell Investments Group
66
Russell Investments Group
United Kingdom
$60M -$4.5M -64,338 -7%
ProShare Advisors
67
ProShare Advisors
Maryland
$58.3M +$3.37M +48,255 +6%
SEI Investments
68
SEI Investments
Pennsylvania
$56.9M -$61.2K -875 -0.1%
HPG
69
Harvest Portfolios Group
Ontario, Canada
$56.9M -$685K -9,798 -1%
Truist Financial
70
Truist Financial
North Carolina
$56.9M +$7.57M +108,262 +15%
PF
71
Phoenix Financial
Israel
$56.7M -$24.1M -344,407 -30%
Aberdeen Group
72
Aberdeen Group
United Kingdom
$55.6M +$1.1M +15,793 +2%
Bank of Montreal
73
Bank of Montreal
Ontario, Canada
$54.7M -$102M -1,452,771 -65%
Capital Research Global Investors
74
Capital Research Global Investors
California
$54.3M +$432K +6,185 +0.8%
ZIC
75
ZWJ Investment Counsel
Georgia
$53.4M +$989K +14,151 +2%
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