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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
Stifel Financial
51
Stifel Financial
Missouri
$88.1M -$3.68M -25,446 -4%
Principal Financial Group
52
Principal Financial Group
Iowa
$88.1M +$52.3M +361,195 +152%
Point72 Asset Management
53
Point72 Asset Management
Connecticut
$87.3M +$8.25M +57,021 +11%
NC
54
Nicholas Company
Wisconsin
$85.3M
PF
55
Phoenix Financial
Israel
$85M -$5.66M -39,107 -6%
Lazard Asset Management
56
Lazard Asset Management
New York
$83M +$15.2M +105,014 +23%
TD Asset Management
57
TD Asset Management
Ontario, Canada
$81.5M -$11.8M -81,368 -13%
State Street
58
State Street
Massachusetts
$73.4M -$14.6M -100,613 -17%
Bank of New York Mellon
59
Bank of New York Mellon
New York
$73.1M +$5.03M +34,778 +8%
EAM
60
Erste Asset Management
Austria
$70.7M
Millennium Management
61
Millennium Management
New York
$69.9M -$141M -973,345 -67%
Russell Investments Group
62
Russell Investments Group
United Kingdom
$67.8M +$2.2M +15,236 +3%
Alyeska Investment Group
63
Alyeska Investment Group
Illinois
$66.5M -$154M -1,061,256 -70%
First Trust Advisors
64
First Trust Advisors
Illinois
$65.6M -$6.27M -43,337 -9%
LPL Financial
65
LPL Financial
California
$64.9M +$12M +82,949 +23%
CCM
66
Causeway Capital Management
California
$63.1M +$1.88M +13,009 +3%
HPG
67
Harvest Portfolios Group
Ontario, Canada
$60.6M +$715K +4,942 +1%
Balyasny Asset Management
68
Balyasny Asset Management
Illinois
$60.1M +$11.9M +82,158 +25%
SEI Investments
69
SEI Investments
Pennsylvania
$59.9M +$3.77M +26,050 +7%
Citigroup
70
Citigroup
New York
$58M -$2.48M -17,116 -4%
ProShare Advisors
71
ProShare Advisors
Maryland
$57.7M +$7.03M +48,612 +14%
Aberdeen Group
72
Aberdeen Group
United Kingdom
$57.3M -$45M -310,849 -44%
Assenagon Asset Management
73
Assenagon Asset Management
Luxembourg
$56.9M -$5.4M -37,357 -9%
Capital Research Global Investors
74
Capital Research Global Investors
California
$56.7M +$220K +1,520 +0.4%
ZIC
75
ZWJ Investment Counsel
Georgia
$55.1M +$1.35M +9,310 +3%

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.