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AstraZeneca
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Overview Fund Activity

1,234 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 518 increasing their positions, 372 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,234
Holders Change
+27
Holders Change %
+2.24%
% of All Funds
16.76%
Holding in Top 10
21
Holding in Top 10 Change
+8
Holding in Top 10 Change %
+61.54%
% of All Funds
0.29%
New
151
Increased
518
Reduced
372
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M

Top Buyers

1
Fisher Asset Management
Fisher Asset Management
Washington
+$677M
2
Bank of America
Bank of America
North Carolina
+$574M
3
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
+$182M
4
American Century Companies
American Century Companies
Missouri
+$119M
5
Franklin Resources
Franklin Resources
California
+$119M

Top Sellers

1
Capital International Investors
Capital International Investors
California
-$458M
2
Fayez Sarofim & Co
Fayez Sarofim & Co
Texas
-$452M
3
Jennison Associates
Jennison Associates
New York
-$358M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$240M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$230M
Name Holding Trade Value Shares
Change 		Shares
Change %
Stifel Financial
51
Stifel Financial
Missouri
$88.1M -$3.74M -50,893 -4%
Principal Financial Group
52
Principal Financial Group
Iowa
$88.1M +$53.1M +722,390 +152%
Point72 Asset Management
53
Point72 Asset Management
Connecticut
$87.3M +$8.38M +114,042 +11%
NC
54
Nicholas Company
Wisconsin
$85.3M – – –
PF
55
Phoenix Financial
Israel
$85M -$5.75M -78,215 -6%
Lazard Asset Management
56
Lazard Asset Management
New York
$83M +$15.4M +210,028 +23%
TD Asset Management
57
TD Asset Management
Ontario, Canada
$81.5M -$12M -162,735 -13%
State Street
58
State Street
Massachusetts
$73.4M -$14.8M -201,227 -17%
Bank of New York Mellon
59
Bank of New York Mellon
New York
$73.1M +$5.11M +69,557 +8%
EAM
60
Erste Asset Management
Austria
$70.7M – – –
Millennium Management
61
Millennium Management
New York
$69.9M -$143M -1,946,689 -67%
Russell Investments Group
62
Russell Investments Group
United Kingdom
$67.8M +$2.24M +30,472 +3%
Alyeska Investment Group
63
Alyeska Investment Group
Illinois
$66.5M -$156M -2,122,511 -70%
First Trust Advisors
64
First Trust Advisors
Illinois
$65.6M -$6.37M -86,674 -9%
LPL Financial
65
LPL Financial
California
$64.9M +$12.2M +165,899 +23%
CCM
66
Causeway Capital Management
California
$63.1M +$1.91M +26,017 +3%
HPG
67
Harvest Portfolios Group
Ontario, Canada
$60.6M +$726K +9,883 +1%
Balyasny Asset Management
68
Balyasny Asset Management
Illinois
$60.1M +$12.1M +164,316 +25%
SEI Investments
69
SEI Investments
Pennsylvania
$59.9M +$3.83M +52,100 +7%
Citigroup
70
Citigroup
New York
$58M -$2.52M -34,233 -4%
ProShare Advisors
71
ProShare Advisors
Maryland
$57.7M +$7.15M +97,224 +14%
Aberdeen Group
72
Aberdeen Group
United Kingdom
$57.3M -$45.7M -621,698 -44%
Assenagon Asset Management
73
Assenagon Asset Management
Luxembourg
$56.9M -$5.49M -74,715 -9%
Capital Research Global Investors
74
Capital Research Global Investors
California
$56.7M +$223K +3,040 +0.4%
ZIC
75
ZWJ Investment Counsel
Georgia
$55.1M +$1.37M +18,619 +3%
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