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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
IUHSA
701
Itau Unibanco Holding S.A.
Brazil
$519K -$1.54M -10,652 -75%
PP
702
Prospector Partners
Connecticut
$519K
FHA
703
First Horizon Advisors
Tennessee
$518K +$85.1K +588 +20%
NG
704
Norden Group
Utah
$518K -$181K -1,251 -26%
AFA
705
AA Financial Advisors
Ohio
$517K -$48.9K -338 -9%
HCM
706
Howland Capital Management
Massachusetts
$515K -$138K -954 -21%
AAI
707
American Assets Inc
California
$515K +$36.2K +250 +8%
CI
708
Corient IA
Florida
$515K +$506K +3,500 New
FIM
709
Fruth Investment Management
Texas
$514K -$7.23K -50 -1%
First Manhattan
710
First Manhattan
New York
$513K +$43.3K +299 +9%
SS
711
SBI Securities
Japan
$502K +$54.4K +376 +12%
CA
712
Crumly & Associates
Illinois
$501K -$18.8K -130 -4%
TW
713
Traveka Wealth
California
$499K +$77.3K +534 +19%
BHPW
714
Beverly Hills Private Wealth
California
$497K -$7.23K -50 -1%
FDP
715
Financiere des Professionnels
Quebec, Canada
$497K -$123K -851 -20%
Koshinski Asset Management
716
Koshinski Asset Management
Illinois
$496K -$13K -90 -3%
PCM
717
Pointe Capital Management
Michigan
$495K
Amundi
718
Amundi
France
$492K -$1.85M -12,818 -79%
FPAS
719
Focus Partners Advisor Solutions
Missouri
$491K +$119K +821 +33%
ACA
720
Aptus Capital Advisors
Alabama
$491K +$24.3K +168 +5%
FFN
721
Focus Financial Network
Minnesota
$490K +$21.1K +146 +5%
BFS
722
Bradley Foster & Sargent
Connecticut
$486K
UOC
723
UBS O'Connor
Illinois
$486K -$3.97M -27,418 -89%
KP
724
Keel Point
Alabama
$480K -$723 -5 -0.2%
ATC
725
Argent Trust Co
Tennessee
$480K -$2.03K -14 -0.4%

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.