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AstraZeneca

1,249 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 521 increasing their positions, 375 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $855M | Put options by funds: $294M

69% more funds holding in top 10

Funds holding in top 10: 1322 (+9)

61% more first-time investments, than exits

New positions opened: 151 | Existing positions closed: 94

39% more repeat investments, than reductions

Existing positions increased: 521 | Existing positions reduced: 375

10% more capital invested

Capital invested by funds: $34.2B → $37.6B (+$3.47B)

3% more funds holding

Funds holding: 1,2181,249 (+31)

0.28% less ownership

Funds ownership: 16.58%16.3% (-0.28%)

Holders
1,249
Holders Change
+31
Holders Change %
+2.55%
% of All Funds
16.75%
Holding in Top 10
22
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+69.23%
% of All Funds
0.29%
New
151
Increased
521
Reduced
375
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M
Name Holding Trade Value Shares
Change
Change in
Stake
HFM
551
Hartford Funds Management
Pennsylvania
$947K +$119K +823 +15%
HKAM
552
Horizon Kinetics Asset Management
New York
$945K -$1.45K -10 -0.2%
VIM
553
VELA Investment Management
Ohio
$944K -$122K -846 -12%
SMH
554
Sanders Morris Harris
Texas
$940K
FIM
555
Freedom Investment Management
Connecticut
$939K -$13.7K -95 -1%
GBT
556
Grove Bank & Trust
Florida
$933K +$148K +1,023 +19%
AG
557
Advocate Group
Minnesota
$932K
DBG
558
De Burlo Group
Massachusetts
$929K -$28.9K -200 -3%
SC
559
Savant Capital
Illinois
$916K -$2.41M -16,682 -73%
FAIM
560
Financial Advocates Investment Management
Washington
$913K -$40.8K -282 -4%
SRC
561
Sage Rhino Capital
California
$901K +$28.6K +198 +3%
FT
562
Fiduciary Trust
Massachusetts
$900K +$74.2K +513 +9%
IC
563
Inscription Capital
Texas
$900K +$961K +6,642 New
SSG
564
Summit Securities Group
New York
$899K +$844K +5,834 +2,061%
Calamos Advisors
565
Calamos Advisors
Illinois
$896K +$3.33K +23 +0.4%
FAM
566
Flaharty Asset Management
Florida
$889K
KWM
567
Kingsview Wealth Management
Oregon
$888K -$14.6K -101 -2%
EFMC
568
Empire Financial Management Company
New York
$882K -$23.4K -162 -3%
CI
569
Cherokee Insurance
Michigan
$882K
RG
570
Rathbones Group
United Kingdom
$881K
AF
571
Allworth Financial
California
$875K -$13.2K -91 -1%
HH
572
Hilltop Holdings
Texas
$874K +$67.9K +469 +9%
CC
573
Callan Capital
California
$872K +$130K +901 +18%
DCM
574
Driehaus Capital Management
Illinois
$870K
VVP
575
Venture Visionary Partners
Ohio
$866K -$1.45K -10 -0.2%

AZN Hedge Fund Activity: Q1 2025 in Review

1,249 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in AstraZeneca (AZN) for Q1 2025, worth a combined $37.6B — up 10% from $34.2B a quarter earlier.

Buyers outnumbered sellers: 151 funds opened new AZN positions and 94 closed out — a net gain of 57 holders — while 521 added to existing stakes and 375 trimmed.

The largest buyer was Fisher Asset Management, adding an estimated $666M. The largest seller was Capital International Investors, cutting an estimated $450M.

  • 1,249 institutional investors held AstraZeneca (AZN) as of Q1 2025, up from 1,218 in Q4 2024.
  • Funds reported $37.6B of AstraZeneca stock for Q1 2025, up 10% quarter-over-quarter.
  • 151 funds opened new AstraZeneca positions in Q1 2025 and 94 closed out, a net change of +57 holders.
  • The largest AstraZeneca buyer in Q1 2025 was Fisher Asset Management, an estimated $666M added.
  • The largest AstraZeneca seller in Q1 2025 was Capital International Investors, an estimated $450M sold.

Based on aggregated 13F filings for Q1 2025.