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AstraZeneca
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Overview Fund Activity

1,234 hedge funds and large institutions have $37.6B invested in AstraZeneca in 2025 Q1 according to their latest regulatory filings, with 151 funds opening new positions, 518 increasing their positions, 372 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,234
Holders Change
+27
Holders Change %
+2.24%
% of All Funds
16.76%
Holding in Top 10
21
Holding in Top 10 Change
+8
Holding in Top 10 Change %
+61.54%
% of All Funds
0.29%
New
151
Increased
518
Reduced
372
Closed
94
Calls
$855M
Puts
$294M
Net Calls
+$561M
Net Calls Change
+$424M

Top Buyers

1
Fisher Asset Management
Fisher Asset Management
Washington
+$677M
2
Bank of America
Bank of America
North Carolina
+$574M
3
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
+$182M
4
American Century Companies
American Century Companies
Missouri
+$119M
5
Franklin Resources
Franklin Resources
California
+$119M

Top Sellers

1
Capital International Investors
Capital International Investors
California
-$458M
2
Fayez Sarofim & Co
Fayez Sarofim & Co
Texas
-$452M
3
Jennison Associates
Jennison Associates
New York
-$358M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$240M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$230M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fayez Sarofim & Co
26
Fayez Sarofim & Co
Texas
$272M -$452M -2,273,140 -62%
Arrowstreet Capital
27
Arrowstreet Capital
Massachusetts
$264M +$182M +2,474,526 +222%
ClearBridge Investments
28
ClearBridge Investments
New York
$256M +$1.79M +24,393 +0.7%
Swedbank
29
Swedbank
Sweden
$248M +$40M +544,418 +19%
Wells Fargo
30
Wells Fargo
California
$230M -$6M -81,617 -3%
MNA
31
Manning & Napier Advisors
New York
$225M -$50.7M -690,303 -18%
SFM
32
Soros Fund Management
New York
$202M -$30.4M -413,303 -13%
Royal Bank of Canada
33
Royal Bank of Canada
Ontario, Canada
$186M +$7.1M +96,583 +4%
Raymond James Financial
34
Raymond James Financial
Florida
$169M -$8.54M -116,167 -5%
Natixis Advisors
35
Natixis Advisors
Massachusetts
$164M +$12.9M +175,813 +9%
Bank of Montreal
36
Bank of Montreal
Ontario, Canada
$164M +$88.8M +1,208,800 +118%
VOYA Investment Management
37
VOYA Investment Management
Georgia
$162M +$32.6M +443,795 +25%
AllianceBernstein
38
AllianceBernstein
Tennessee
$161M -$67.2M -914,344 -29%
Janus Henderson Group
39
Janus Henderson Group
United Kingdom
$160M +$9.08M +122,982 +6%
Citadel Advisors
40
Citadel Advisors
Florida
$150M -$160M -2,176,596 -52%
American Century Companies
41
American Century Companies
Missouri
$149M +$119M +1,621,974 +407%
EIP
42
Epoch Investment Partners
New York
$147M -$2.22M -30,212 -1%
UBS Group
43
UBS Group
Switzerland
$126M -$157M -2,140,899 -56%
D.E. Shaw & Co
44
D.E. Shaw & Co
New York
$125M -$230M -3,128,538 -65%
SC
45
Saturna Capital
Washington
$120M -$91.9K -1,250 -0.1%
CIC
46
Crawford Investment Counsel
Georgia
$115M -$3.46M -47,069 -3%
GQG Partners
47
GQG Partners
Florida
$107M -$214M -2,918,310 -67%
Marshall Wace
48
Marshall Wace
United Kingdom
$101M -$184M -2,500,932 -65%
Deutsche Bank
49
Deutsche Bank
Germany
$90.8M +$78.7M +1,070,223 +650%
Parnassus Investments
50
Parnassus Investments
California
$90M +$3.36M +45,741 +4%
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