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AstraZeneca

1,391 hedge funds and large institutions have $45.2B invested in AstraZeneca in 2025 Q4 according to their latest regulatory filings, with 256 funds opening new positions, 497 increasing their positions, 410 reducing their positions, and 119 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,391
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
21
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$597M
Puts
$420M
Net Calls
Net Calls Change

Top Buyers

1 +$420M
2 +$412M
3 +$327M
4
Citigroup
Citigroup
New York
+$204M
5
Barclays
Barclays
United Kingdom
+$180M

Top Sellers

1 -$924M
2 -$831M
3 -$550M
4
Primecap Management
Primecap Management
California
-$258M
5
Citadel Advisors
Citadel Advisors
Florida
-$241M
Name Holding Trade Value Shares
Change
Change in
Stake
VA
326
Vident Advisory
Georgia
$4.56M
RAM
327
Ramirez Asset Management
New York
$4.53M
DC
328
Davenport & Co
Virginia
$4.51M
SCM
329
Seascape Capital Management
New Hampshire
$4.44M
CW
330
Channel Wealth
California
$4.41M
MLL
331
Moody Lynn & Lieberson
Massachusetts
$4.4M
DWM
332
Dynasty Wealth Management
Florida
$4.37M
JIR
333
James Investment Research
Ohio
$4.34M
SVWAG
334
Sound View Wealth Advisors Group
Georgia
$4.33M
William Blair Investment Management
335
William Blair Investment Management
Illinois
$4.33M
ANTB
336
AMG National Trust Bank
Colorado
$4.29M
AF
337
Aviso Financial
Ontario, Canada
$4.26M
CP
338
Clayton Partners
California
$4.24M
Credit Agricole
339
Credit Agricole
France
$4.11M
DA
340
DCF Advisers
Connecticut
$4.07M
CG
341
Caprock Group
Idaho
$4.04M
HFM
342
Harvest Fund Management
China
$4.01M
MMA
343
Miracle Mile Advisors
California
$4.01M
GH
344
GAM Holding
Switzerland
$3.93M
AWA
345
Arkadios Wealth Advisors
Georgia
$3.92M
AFG
346
Atomi Financial Group
New York
$3.91M
Pacer Advisors
347
Pacer Advisors
Pennsylvania
$3.89M
NI
348
Natural Investments
California
$3.83M
D.E. Shaw & Co
349
D.E. Shaw & Co
New York
$3.81M
MAM
350
Madison Asset Management
Wisconsin
$3.73M