|
1
|
|
$343M
|
-$12.7M
|
-138,192
|
-3%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$330M
|
-$8.54M
|
-92,866
|
-2%
|
|
|
3
|
|
$299M
|
+$12.4M
|
+135,015
|
+4%
|
|
|
4
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$124M
|
-$81.9M
|
-891,094
|
-38%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$117M
|
+$31.5M
|
+342,064
|
+33%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$84.6M
|
-$8.06M
|
-87,641
|
-8%
|
|
|
7
|
RA Capital Management
Boston,
Massachusetts
|
$84.6M
|
–
|
–
|
–
|
|
|
8
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$81.6M
|
-$2.87M
|
-31,240
|
-3%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$80.1M
|
+$2.8M
|
+30,443
|
+3%
|
|
|
10
|
Geode Capital Management
Boston,
Massachusetts
|
$77.2M
|
+$375K
|
+4,079
|
+0.4%
|
|
|
11
|
Eventide Asset Management
Boston,
Massachusetts
|
$70.1M
|
+$75.8K
|
+824
|
+0.1%
|
|
|
12
|
Alethea Capital Management
Mercer Island,
Washington
|
$62.1M
|
-$385K
|
-4,186
|
-0.6%
|
|
|
13
|
|
$58.6M
|
+$6.19M
|
+67,285
|
+11%
|
|
|
14
|
Wellington Management Group
Boston,
Massachusetts
|
$57M
|
-$6.4M
|
-69,588
|
-9%
|
|
|
15
|
Perceptive Advisors
New York
|
$56.2M
|
-$10.9M
|
-118,770
|
-15%
|
|
|
16
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$54.6M
|
+$1.81M
|
+19,701
|
+3%
|
|
|
17
|
|
$48.8M
|
+$15.3M
|
+166,708
|
+41%
|
|
|
18
|
Lazard Asset Management
New York
|
$45.5M
|
+$41.5M
|
+451,737
|
+526%
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$41.9M
|
+$17.5M
|
+190,707
|
+63%
|
|
|
20
|
Sofinnova Investments
Menlo Park,
California
|
$41.6M
|
+$10.3M
|
+112,199
|
+30%
|
|
|
21
|
Boxer Capital Management
San Diego,
California
|
$39.8M
|
+$43.2M
|
+470,000
|
New
|
|
|
22
|
PFM Health Sciences
San Francisco,
California
|
$39.5M
|
–
|
–
|
–
|
|
|
23
|
Woodline Partners
San Francisco,
California
|
$34.6M
|
+$10.1M
|
+109,872
|
+37%
|
|
|
24
|
|
$34.1M
|
+$1.08M
|
+11,710
|
+3%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$34.1M
|
+$6.43M
|
+69,918
|
+21%
|
|
