Avadel Pharmaceuticals

AVDL

Market cap $2.12B

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 11th February 2026 2.

DUBLIN--(BUSINESS WIRE)--Alkermes plc (Nasdaq: ALKS) (“Alkermes”) and Avadel Pharmaceuticals plc (Nasdaq: AVDL) (“Avadel”) today announced Alkermes' completion of its acquisition of Avadel, a commercial-stage biopharmaceutical company. The acquisition adds Avadel's FDA-approved product, LUMRYZ®, to Alkermes' commercial portfolio, and provides Alkermes with a commercial organization experienced in this disease state. This strategic move accelerates Alkermes' entry into the sleep medicine market.

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 10th February 2026 2.

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF THAT JURISDICTION.

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 09th February 2026 2.

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 06th February 2026 2.

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 05th February 2026 2.

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 04th February 2026 2.

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 03rd February 2026 2.

FORM 8.3 IRISH TAKEOVER PANEL DISCLOSURE UNDER RULE 8.3 OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2013 DEALINGS BY PERSONS WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE 1. KEY INFORM A TION Name of person dealing (Note 1) State Street Global Advisors & Affiliates Company dealt in Avadel Pharmaceuticals plc Class of relevant security to which the dealings being disclosed relate (Note 2) $0.01 ordinary shares Date of dealing 02nd February 2026 2.