|
1
|
First Eagle Investment Management
New York
|
$44.5M
|
–
|
–
|
–
|
|
|
2
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$33.5M
|
–
|
–
|
–
|
|
|
3
|
|
$23.9M
|
+$6.9M
|
+1,808,657
|
+27%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$17.3M
|
+$1.54M
|
+402,516
|
+7%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$15.1M
|
-$2.01M
|
-525,639
|
-9%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$12.6M
|
-$1.96M
|
-514,093
|
-10%
|
|
|
7
|
Millennium Management
New York
|
$11M
|
-$9.07M
|
-2,376,004
|
-37%
|
|
|
8
|
NEA Management Company
Timonium,
Maryland
|
$6.98M
|
–
|
–
|
–
|
|
|
9
|
Sphera Funds Management
Tel Aviv,
Israel
|
$5.63M
|
+$105K
|
+27,400
|
+1%
|
|
|
10
|
Northern Trust
Chicago,
Illinois
|
$3.46M
|
-$12.6K
|
-3,315
|
-0.3%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$3.29M
|
+$60.1K
|
+15,739
|
+1%
|
|
|
12
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$3.23M
|
+$45.8K
|
+12,001
|
+1%
|
|
|
13
|
Eventide Asset Management
Boston,
Massachusetts
|
$2.95M
|
+$4.07M
|
+1,066,000
|
New
|
|
|
14
|
Handelsbanken Fonder
Stockholm,
Sweden
|
$2.77M
|
–
|
–
|
–
|
|
|
15
|
Menora Mivtachim Holdings
Ramat Gan,
Israel
|
$2.71M
|
–
|
–
|
–
|
|
|
16
|
TIAA CREF Investment Management
New York
|
$1.88M
|
-$6.66K
|
-1,745
|
-0.3%
|
|
|
17
|
Charles Schwab
San Francisco,
California
|
$1.78M
|
+$302K
|
+79,262
|
+14%
|
|
|
18
|
|
$1.62M
|
+$2.02M
|
+528,836
|
+954%
|
|
|
19
|
|
$1.53M
|
+$1.4M
|
+367,631
|
+199%
|
|
|
20
|
DAFNA Capital Management
Los Angeles,
California
|
$1.27M
|
+$38.2K
|
+10,000
|
+2%
|
|
|
21
|
Two Sigma Investments
New York
|
$1.25M
|
+$1.2M
|
+314,491
|
+229%
|
|
|
22
|
Bridgeway Capital Management
Houston,
Texas
|
$1.18M
|
+$152K
|
+39,835
|
+10%
|
|
|
23
|
Bank of New York Mellon
New York
|
$1.1M
|
+$310K
|
+81,244
|
+26%
|
|
|
24
|
California Public Employees Retirement System
Sacramento,
California
|
$1.09M
|
+$708K
|
+185,551
|
+89%
|
|
|
25
|
Oxford Asset Management
Oxford,
United Kingdom
|
$1.04M
|
-$364K
|
-95,269
|
-20%
|
|
