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Aquestive Therapeutics
AQST

176 hedge funds and large institutions have $466M invested in Aquestive Therapeutics in 2025 Q4 according to their latest regulatory filings, with 45 funds opening new positions, 68 increasing their positions, 38 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

114% more first-time investments, than exits

New positions opened: 45 | Existing positions closed: 21

79% more repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 38

33% more funds holding in top 10

Funds holding in top 10: 3 → 4 (+1)

26% more capital invested

Capital invested by funds: $369M → $466M (+$96.4M)

16% more funds holding

Funds holding: 152 → 176 (+24)

11% more call options, than puts

Call options by funds: $12.6M | Put options by funds: $11.4M

7.13% less ownership

Funds ownership: 66.24% → 59.11% (-7.1%)

Holders
176
Holders Change
+24
Holders Change %
+15.79%
% of All Funds
2.14%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
45
Increased
68
Reduced
38
Closed
21
Calls
$12.6M
Puts
$11.4M
Net Calls
+$1.27M
Net Calls Change
-$2.59M

Top Buyers

1
BlackRock
BlackRock
New York
+$7.79M
2
Federated Hermes
Federated Hermes
Pennsylvania
+$7.78M
3
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
+$7.19M
4
Wells Fargo
Wells Fargo
California
+$6.59M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$6.05M

Top Sellers

1
PA
Perceptive Advisors
New York
-$18.8M
2
BOCH
Blue Owl Capital Holdings
New York
-$4.52M
3
NCM
Nantahala Capital Management
Connecticut
-$3.35M
4
SCM
Sio Capital Management
New York
-$3.15M
5
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$3.12M
Name Holding Trade Value Shares
Change 		Change in
Stake
BCM
1
Bratton Capital Management
Texas
$63.4M – – –
BlackRock
2
BlackRock
New York
$50.2M +$7.79M +1,249,719 +19%
RI
3
RTW Investments
New York
$40.4M – – –
Vanguard Group
4
Vanguard Group
Pennsylvania
$38.1M +$1.43M +230,202 +4%
EC
5
EcoR1 Capital
California
$17M – – –
SB
6
Samsara BioCapital
California
$16.1M – – –
State Street
7
State Street
Massachusetts
$15.9M +$5.36M +860,562 +54%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$15.3M +$1.75M +280,144 +13%
Federated Hermes
9
Federated Hermes
Pennsylvania
$13.1M +$7.78M +1,249,044 +159%
Morgan Stanley
10
Morgan Stanley
New York
$11.4M +$2.17M +348,641 +25%
Millennium Management
11
Millennium Management
New York
$9.92M +$1.53M +246,040 +19%
Bank of America
12
Bank of America
North Carolina
$7.8M -$90.6K -14,544 -1%
Wells Fargo
13
Wells Fargo
California
$7.68M +$6.59M +1,057,145 +805%
BNP Paribas Financial Markets
14
BNP Paribas Financial Markets
France
$7.57M +$7.19M +1,153,175 +6,233%
Janney Montgomery Scott
15
Janney Montgomery Scott
Pennsylvania
$7.06M -$41.3K -6,633 -0.6%
Commonwealth Equity Services
16
Commonwealth Equity Services
Massachusetts
$6.59M -$243K -38,933 -4%
HF
17
HRT Financial
New York
$6.43M +$2.71M +434,757 +78%
SCM
18
Sio Capital Management
New York
$6.42M -$3.15M -505,000 -34%
Balyasny Asset Management
19
Balyasny Asset Management
Illinois
$6.27M +$6.05M +970,939 New
D.E. Shaw & Co
20
D.E. Shaw & Co
New York
$6.08M +$5.71M +915,697 +3,591%
Goldman Sachs
21
Goldman Sachs
New York
$5.87M +$3.2M +513,914 +130%
Aberdeen Group
22
Aberdeen Group
United Kingdom
$5.23M +$1.15M +184,203 +29%
PA
23
Perceptive Advisors
New York
$4.83M -$18.8M -3,012,906 -80%
Northern Trust
24
Northern Trust
Illinois
$4.8M +$373K +59,926 +9%
WA
25
Wasatch Advisors
Utah
$4.4M -$268K -43,038 -6%
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